Shigenaga Y, Chen I C, Suemune S, Nishimori T, Nasution I D, Yoshida A, Sato H, Okamoto T, Sera M, Hosoi M
J Comp Neurol. 1986 Jan 15;243(3):388-408. doi: 10.1002/cne.902430309.
Transganglionic transport of HRP was used to study the patterns of termination of somatic afferent fibers innervating oral and facial structures within the trigeminal nucleus caudalis and upper cervical dorsal horn of the cat. In separate animals, the superior alveolar, pterygopalatine, buccal, inferior alveolar, lingual, frontal, corneal, zygomatic, infraorbital, mental, mylohyoid, and auriculotemporal branches of the trigeminal nerve were traced in this experiment. The organization of the primary afferents innervating the oral structures is not uniform across laminae and at different rostrocaudal levels of the nucleus caudalis. The superior alveolar and pterygopalatine nerves mainly terminate in laminae I, II, and V at the level of the rostral one-third of the caudalis. By contrast, the lingual, inferior alveolar, and buccal nerve terminate in laminae I-V of, respectively, the rostral third, the entire length, and caudal two-thirds of the caudalis. In addition, the lingual, buccal, and pterygopalatine nerves terminate in the dorsal and middle parts of the interstitial islands or pockets of lamina I neuropil extending to the rostral levels parallel to the nucleus interpolaris. Mediolaterally, in laminae I, II, and V of the rostral third an extensive overlap of projections was found between the branches from each trigeminal division, and some overlap was observed between projections from the mandibular and maxillary divisions. On the other hand, the projections of primary afferents innervating the facial structures are arranged in a somatotopic fashion in rostrocaudal and mediolateral axes over the laminae (I-IV) through the nucleus caudalis and upper cervical dorsal horn. Fibers from the perioral and perinasal regions terminate most rostrally in caudalis, and fibers from progressively more posterior facial regions terminate at successively lower levels. A mediolateral somatotopic arrangement was observed, with fibers from the ventral parts of face ending in the medial regions and fibers from the progressively more dorsal parts of the face ending in successively more lateral regions of the medullary and upper cervical dorsal horns. Corneal afferent terminals are concentrated in the outer parts of lamina II at the levels of the rostral parts of the caudal two-thirds of the caudalis and the interstitial islands of lamina I. The maxillary division terminates first at the most caudal level of the caudalis, followed by the ophthalmic division descending as far as the C2 segment and the mandibular division reaching the most caudal level of the C2 segment.(ABSTRACT TRUNCATED AT 400 WORDS)
运用辣根过氧化物酶的跨节运输来研究支配猫三叉神经尾侧核及上颈段背角内口腔和面部结构的躯体传入纤维的终末模式。在不同的动物身上，本实验追踪了三叉神经的上牙槽、翼腭、颊、下牙槽、舌、额、角膜、颧、眶下、颏、下颌舌骨及耳颞支。支配口腔结构的初级传入纤维在尾侧核的各层及不同的前后水平上组织分布并不均匀。上牙槽神经和翼腭神经主要终止于尾侧核前三分之一水平的Ⅰ、Ⅱ和Ⅴ层。相比之下，舌神经、下牙槽神经和颊神经分别终止于尾侧核前三分之一、全长及后三分之二的Ⅰ - Ⅴ层。此外，舌神经、颊神经和翼腭神经终止于Ⅰ层神经毡的间隙岛或袋的背侧和中间部分，这些间隙岛或袋延伸至与极间核平行的头端水平。在尾侧核前三分之一的Ⅰ、Ⅱ和Ⅴ层，从三叉神经各分支发出的投射在内外侧有广泛重叠，并且在下颌支和上颌支的投射之间也观察到一些重叠。另一方面，支配面部结构的初级传入纤维在尾侧核及上颈段背角的各层（Ⅰ - Ⅳ），在前后轴和内外侧轴上呈躯体定位排列。来自口周和鼻周区域的纤维在尾侧核中最靠头端处终止，而来自面部越靠后的区域的纤维则在依次更低的水平终止。观察到了内外侧躯体定位排列，来自面部腹侧部分的纤维终止于内侧区域，而来自面部越靠背侧部分的纤维则依次终止于延髓和上颈段背角的更外侧区域。角膜传入终末集中在尾侧核后三分之二头端部分水平的Ⅱ层外侧部分以及Ⅰ层的间隙岛。上颌支首先在尾侧核的最尾端水平终止，随后眼支下行至C2节段，下颌支则到达C2节段的最尾端水平。（摘要截断于400字）
