Department of Ophthalmology, Korea University College of Medicine, 73, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
Sci Rep. 2024 Nov 5;14(1):26762. doi: 10.1038/s41598-024-77572-7.
This study aimed to investigate the short-term variability of ocular biometric measurements and to analyze the factors associated with high variability of biometric values in patients with cataract. This retrospective study included 60 eyes of 60 patients who underwent ocular biometry twice with the IOLMaster 700 (March to November 2023). Ocular surface parameters included tear film break-up time (TBUT), corneal and conjunctival staining scores (CSS/ConSS). Refractive surprise was defined as a mean absolute error exceeding 0.5 diopter (D). Participants included 22 men and 38 women with a mean age of 70.6 ± 8.4 years. The variability of mean keratometric (K) values and astigmatism showed notable variability compared to axial length (mean K: 0.18 ± 0.17D, astigmatism: 0.21 ± 0.26D, axial length: 0.01 ± 0.01 mm). A decreased TBUT and increased CSS were significantly associated with high variability (≥ 0.25D) of mean K (p = 0.040/0.008). The high K variability group (≥ 0.25D) revealed a significantly higher incidence of refractive surprise (> 0.5D) compared with the low K variability group (< 0.25D) (45.5%/17.9%, p = 0.037). Preoperative lower TBUT and higher CSS influenced the variability of K values in ocular biometry and may be related with postoperative refractive surprise due to erroneous K values.
本研究旨在探讨眼生物测量的短期可变性，并分析白内障患者生物测量值高度可变性的相关因素。这是一项回顾性研究，纳入了 2023 年 3 月至 11 月期间在 IOLMaster 700 上接受两次眼部生物测量的 60 例 60 眼患者。眼部表面参数包括泪膜破裂时间（TBUT）、角膜和结膜染色评分（CSS/ConSS）。屈光意外定义为平均绝对误差超过 0.5 屈光度（D）。参与者包括 22 名男性和 38 名女性，平均年龄为 70.6±8.4 岁。与眼轴长度相比，平均角膜曲率（K）值和散光的可变性显示出明显的可变性（平均 K：0.18±0.17D，散光：0.21±0.26D，眼轴长度：0.01±0.01mm）。TBUT 减少和 CSS 增加与平均 K 值的高度可变性（≥0.25D）显著相关（p=0.040/0.008）。与低 K 可变性组（<0.25D）相比，高 K 可变性组（≥0.25D）的屈光意外发生率（>0.5D）显著更高（45.5%/17.9%，p=0.037）。术前较低的 TBUT 和较高的 CSS 影响眼生物测量中的 K 值变异性，并且可能与错误的 K 值导致术后屈光意外有关。
