Monzio-Compagnoni Nicola, Zuccon Gianmarco, Barbosa Fabiane, Rampoldi Antonio Gaetano, Tolva Valerio Stefano
Department of Vascular Surgery, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Fondazione Centro Cardiologia e Cardiochirurgia A. De Gasperis, Milan, Italy.
Int J Angiol. 2023 Jul 25;33(4):282-287. doi: 10.1055/s-0043-1771344. eCollection 2024 Dec.
Type 2 endoleak has been proved not to significantly increase the risk of aneurysm rupture. However, it is associated with aneurysm enlargement and may require secondary interventions. Its role has been widely investigated, but a definitive consensus about its management has still not been obtained. We performed a retrospective, single-center observational study that investigates the incidence of type 2 endoleak and its implications in the long-term follow-up in all the patients who underwent endovascular aortic repair (EVAR) for abdominal aortic aneurysm from 2011 to 2016 at our institution. A total of 216 patients who underwent EVAR during the specified time period were enrolled, and 85 of them (39%) developed type 2 endoleak in their follow-up. Thirty-one of the patients who developed type 2 endoleak faced an aneurysm sac growth > 10 mm and required secondary intervention. Only nine of them showed resolution of the leak. In the long-term follow-up, patients who developed type 2 endoleak after EVAR did not show a significantly increased mortality compared with those who did not, but some of them required late open conversion due to aneurysm sac enlargement and some other developed a secondary type 1 endoleak which required correction. The management of type 2 endoleak remains debated, despite consensus exist regarding the need for intervention when a > 10-mm aneurysm sac growth is observed. Further studies are necessary to better define which are the "high-risk" type 2 endoleaks and identify the patients who would benefit more from correction.
已证实Ⅱ型内漏不会显著增加动脉瘤破裂风险。然而,它与动脉瘤增大有关,可能需要二次干预。其作用已得到广泛研究,但对于其治疗仍未达成明确共识。我们进行了一项回顾性单中心观察性研究,调查了2011年至2016年在我院接受腹主动脉瘤血管内修复术(EVAR)的所有患者中Ⅱ型内漏的发生率及其在长期随访中的影响。在指定时间段内共纳入216例行EVAR的患者,其中85例(39%)在随访中发生Ⅱ型内漏。发生Ⅱ型内漏的患者中有31例动脉瘤囊增大超过10 mm,需要二次干预。其中只有9例漏口消失。在长期随访中,EVAR术后发生Ⅱ型内漏的患者与未发生Ⅱ型内漏的患者相比,死亡率没有显著增加,但其中一些患者因动脉瘤囊增大需要后期开放转换,还有一些患者发生了需要纠正的继发Ⅰ型内漏。尽管对于观察到动脉瘤囊增大超过10 mm时需要干预已达成共识,但Ⅱ型内漏的治疗仍存在争议。有必要进行进一步研究,以更好地确定哪些是“高危”Ⅱ型内漏,并确定哪些患者从纠正中获益更多。