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巴基斯坦代谢性肥胖正常体重个体的内脏脂肪指数(VAI)与内脏体脂的关系。

Relationship of visceral adiposity index (VAI) and visceral body fat among metabolically obese normal weight individuals from Pakistan.

作者信息

Ishfaq Faisal, Iqtadar Somia, Lodhi Sidrah, Kanwal Sibgha, Amir Hira, Ishfaq Arslan, Ishfaq Asma

机构信息

King Edward Medical University, Lahore, Pakistan.

Fatima Jinnah Medical University, Lahore, Pakistan.

出版信息

Obes Pillars. 2024 Oct 10;12:100140. doi: 10.1016/j.obpill.2024.100140. eCollection 2024 Dec.

DOI:10.1016/j.obpill.2024.100140
PMID:39502573
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11535750/
Abstract

BACKGROUND

An increasing number of people throughout the world are suffering with visceral obesity. Accumulation of visceral fat is a pathogenic manifestation of global fat dysfunction, that leads to inflammation, atherosclerosis, abnormal lipid levels, and high blood pressure.

METHODS

This association study was conducted at Department of Medicine, Mayo Hospital Lahore, Pakistan. 30 participants who meet the selection criteria were recruited after taking written consent. Then patients were evaluated for their height, weight and waist circumference body mass index. Visceral fat was calculated by using machine for bio-impendence analysis. Visceral adiposity index was calculated. 5 cc venous blood sample was' collected under aseptic measures and all samples were sent to the hospital's laboratory for assessment of lipid profile and blood sugar levels.

RESULTS

We have studied 30 patients (43.8 % female and 56.3 % male), mean age of study population calculated was 40.6 ± 11.80 years. The mean Visceral Body Fat was found to be 13.53 ± 1.41, High-Density Lipoprotein cholesterol mean calculated was 36.91 ± 9.18 mg/dL, and mean Visceral Adiposity Index calculated was 16.75 ​± ​7.55. Pearson Correlation was used, to find correlation between Visceral Adiposity Index and Visceral Body fat. The value turned out to be 00.899∗∗ shows positive correlation, p-value was 0. 001 significant.

CONCLUSION

In this study we found positive correlation of visceral adiposity index and visceral body fat by use of Bio impedance analysis machine among metabolically obese normal weight individuals. Visceral adiposity index requires many blood tests while Bio impedance analysis machine can be used in simple outdoor settings hence, we can isolate high risk patient in outdoor settings without any invasive procedures or laboratory investigations.

摘要

背景

全球范围内,越来越多的人患有内脏肥胖症。内脏脂肪堆积是全身脂肪功能障碍的一种致病表现,会导致炎症、动脉粥样硬化、血脂异常和高血压。

方法

这项关联研究在巴基斯坦拉合尔梅奥医院内科进行。在获得书面同意后,招募了30名符合入选标准的参与者。然后对患者的身高、体重和腰围体重指数进行评估。使用生物电阻抗分析仪计算内脏脂肪。计算内脏脂肪指数。在无菌措施下采集5毫升静脉血样本,所有样本均送至医院实验室评估血脂谱和血糖水平。

结果

我们研究了30名患者(女性占43.8%,男性占56.3%),研究人群的平均年龄计算为40.6±11.80岁。发现平均内脏体脂为13.53±1.41,计算出的高密度脂蛋白胆固醇平均为36.91±9.18毫克/分升,计算出的平均内脏脂肪指数为16.75±7.55。使用Pearson相关性分析来寻找内脏脂肪指数与内脏体脂之间的相关性。结果显示为0.899**,呈正相关,p值为0.001,具有显著性。

结论

在本研究中,我们发现在代谢性肥胖的正常体重个体中,通过生物电阻抗分析仪测得内脏脂肪指数与内脏体脂呈正相关。内脏脂肪指数需要多次血液检测,而生物电阻抗分析仪可用于简单的户外环境,因此,我们可以在户外环境中识别高危患者,而无需任何侵入性操作或实验室检查。