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测量体脂、内脏脂肪指数和脂联素指数在预测心血管代谢危险因素中的重要性。

Importance of Measured Body Fat, Visceral Adiposity Index, and Lipid Accumulation Product Index in Predicting Cardiometabolic Risk Factors.

机构信息

Department of Family Medicine, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.

出版信息

Metab Syndr Relat Disord. 2021 Apr;19(3):174-179. doi: 10.1089/met.2020.0098. Epub 2020 Oct 29.

DOI:10.1089/met.2020.0098
PMID:33121374
Abstract

Obesity, which is defined as excessive fat accumulation in the body, is an important public health problem. The aim of this study was to compare measured body fat and the visceral adiposity index (VAI) and lipid accumulation product (LAP) index used to predict cardiometabolic risk (CMR) factors. This study was performed retrospectively by scanning the files of 817 participants who had bioelectrical impedance analysis (BIA) results and routine blood tests. The VAI and the LAP index were calculated using the appropriate formulas. Of the 817 participants included in the study, 67.9% ( = 555) were female, 32.1% ( = 262) were male, and the mean age was 36.14 ± 11.4 (18-65) years. The mean body mass index (BMI) was 29.90 ± 6.6 kg/m and 24.2% ( = 198) of the participants were of normal weight (BMI <25 kg/m), while 75.8% ( = 619) were overweight or obese (BMI ≥25 kg/m). Body fat quantity was higher in females than in males. As BMI increased, the body fat quantity measured by BIA also increased ( < 0.001). The mean LAP index of men was higher than the mean LAP index of women in both the normal-weight group and the obese group ( = 0.025 and  = 0.033, respectively). One unit increase in visceral fat percentage resulted in a 77.9% increase in CMR. It may not be sufficient to use only BMI to predict obesity and related cardiometabolic diseases. According to the study findings, it was determined that the increase in visceral fat percentage significantly increases the CMR.

摘要

肥胖是指体内脂肪过度积累,是一个重要的公共卫生问题。本研究旨在比较用于预测心血管代谢风险(CMR)因素的测量体脂肪和内脏脂肪指数(VAI)和脂质蓄积产物(LAP)指数。本研究通过扫描 817 名具有生物电阻抗分析(BIA)结果和常规血液检查结果的参与者的文件进行回顾性研究。使用适当的公式计算 VAI 和 LAP 指数。在纳入研究的 817 名参与者中,67.9%( = 555)为女性,32.1%( = 262)为男性,平均年龄为 36.14 ± 11.4(18-65)岁。平均体重指数(BMI)为 29.90 ± 6.6 kg/m,24.2%( = 198)的参与者为正常体重(BMI <25 kg/m),而 75.8%( = 619)为超重或肥胖(BMI ≥25 kg/m)。女性的体脂肪量高于男性。随着 BMI 的增加,通过 BIA 测量的体脂肪量也增加( < 0.001)。在正常体重组和肥胖组中,男性的平均 LAP 指数均高于女性( = 0.025 和  = 0.033)。内脏脂肪百分比增加一个单位,CMR 增加 77.9%。仅使用 BMI 来预测肥胖和相关的心血管代谢疾病可能还不够。根据研究结果,确定内脏脂肪百分比的增加显著增加 CMR。

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