Garima S Kukreja, Priyanka S Khopkar-Kale, Srikanth P Tripathy, Jitendra S Bhawalkar
Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research Pimpri, Pune, 411018, India.
Central Research Facility, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed-to-be-University), Pimpri, Pune, 411018, India.
Eur J Clin Microbiol Infect Dis. 2025 Jan;44(1):209-211. doi: 10.1007/s10096-024-04975-9. Epub 2024 Nov 6.
The Oropouche virus (OROV), a member of the Orthobunyavirus genus, poses a significant public health challenge due to its potential for vertical transmission and lack of approved vaccines or antiviral treatments. Recent outbreaks have highlighted the association of OROV infection in pregnant women with severe outcomes, including spontaneous abortions, congenital anomalies, and fetal deaths. This letter to the editor emphasizes the need for a multifaceted approach to address the potential for vertical transmission of OROV, including the use of small animal models, detailed pathological studies, and robust preventive measures. We stress the importance of increased clinician awareness, timely patient management, and a One Health surveillance program to mitigate the risks associated with OROV infection during pregnancy.
奥罗普切病毒（OROV）是正布尼亚病毒属的成员，由于其具有垂直传播的可能性且缺乏经批准的疫苗或抗病毒治疗方法，对公共卫生构成了重大挑战。最近的疫情凸显了孕妇感染OROV与严重后果之间的关联，包括自然流产、先天性异常和胎儿死亡。这封致编辑的信强调需要采取多方面的方法来应对OROV垂直传播的可能性，包括使用小动物模型、详细的病理学研究以及强有力的预防措施。我们强调提高临床医生的认识、及时进行患者管理以及开展“同一健康”监测计划以降低孕期与OROV感染相关风险的重要性。
