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用于小动物超声心动图检查的高频可穿戴超声阵列带

High-Frequency Wearable Ultrasound Array Belt for Small Animal Echocardiography.

作者信息

Zeng Yushun, Sun Xin, Zhang Junhang, Chang Chi-Feng, Liu Baoqiang, Gong Chen, Ji Jie, Zhang Bryan Zhen, Wang Yujie, Xinhu Ren Matthew, Wodnicki Robert, Liu Hsiao-Chuan, Zhou Qifa

出版信息

IEEE Trans Ultrason Ferroelectr Freq Control. 2024 Dec;71(12: Breaking the Resolution Barrier in Ultrasound):1915-1923. doi: 10.1109/TUFFC.2024.3492197. Epub 2025 Jan 8.

Abstract

Wearable ultrasound has been widely developed for long-term, continuous imaging without the need for bulky system manipulation and repeated manual locating. To potentially lead to more accurate and reliable imaging monitoring, this work presents the design, fabrication, and evaluation of a novel high-frequency wearable ultrasound array belt (WUAB) for small animal echocardiography. The fabrication process involved precise dicing technology for a -pitch design. The WUAB consists of two matching layers, a piezoelectric composite with 128 channels, a customized flexible circuit substrate, an acoustic backing layer, and a customized belt structure with designed end tip and insertion point for wearability. The resulting WUAB demonstrates the sensitivity of and the fractional bandwidth (BDW) of . In vivo experiments on rat model showed expected echocardiography and B-mode images of rat heart. These results represent significant promise for future longitudinal studies in small animals and real-time physiological monitoring.

摘要

可穿戴超声技术已得到广泛发展,可实现长期、连续成像,无需进行繁琐的系统操作和反复手动定位。为了有可能实现更准确、可靠的成像监测,本研究展示了一种用于小动物超声心动图的新型高频可穿戴超声阵列带(WUAB)的设计、制造和评估。制造过程涉及用于间距设计的精确切割技术。WUAB由两个匹配层、一个具有128个通道的压电复合材料、一个定制的柔性电路基板、一个声学背衬层以及一个具有设计的末端尖端和插入点以实现可穿戴性的定制带结构组成。所得的WUAB展示了灵敏度和分数带宽(BDW)。在大鼠模型上进行的体内实验显示了大鼠心脏的预期超声心动图和B模式图像。这些结果为未来在小动物身上进行纵向研究和实时生理监测带来了巨大希望。

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High-Frequency Wearable Ultrasound Array Belt for Small Animal Echocardiography.用于小动物超声心动图检查的高频可穿戴超声阵列带
IEEE Trans Ultrason Ferroelectr Freq Control. 2024 Dec;71(12: Breaking the Resolution Barrier in Ultrasound):1915-1923. doi: 10.1109/TUFFC.2024.3492197. Epub 2025 Jan 8.
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IEEE Trans Ultrason Ferroelectr Freq Control. 2022 Dec;69(12):3382-3391. doi: 10.1109/TUFFC.2022.3216602. Epub 2022 Nov 24.
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IEEE Trans Ultrason Ferroelectr Freq Control. 2022 Sep;69(9):2672-2680. doi: 10.1109/TUFFC.2022.3195998. Epub 2022 Aug 26.
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