Lin Hsi-Hsien, Hung Pei-I, Chen Kuan-Jung, Hsiung Wei, Chang Ming-Chau
Department of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China; National Yang Ming Chiao Tung University, School of Medicine, Taiwan, Republic of China.
National Yang Ming Chiao Tung University, School of Medicine, Taiwan, Republic of China; Taipei City Hospital, Ren-Ai Branch, Taipei, Taiwan, Republic of China.
Spine J. 2025 Apr;25(4):727-733. doi: 10.1016/j.spinee.2024.10.019. Epub 2024 Nov 4.
Percutaneous vertebroplasty for the treatment of osteoporotic burst fractures remains controversial. A previous study has shown that an osteoporotic burst fracture with asymptomatic spinal canal compromise is not a contraindication for percutaneous vertebroplasty.
To determine whether these outcomes persist over a long term, we continued to observe patients in their short-term study over a long-term period.
Prospective study.
Patients with osteoporotic vertebral fractures were classified as Dennis type I and II and AO type A1-A4, and no neurological deficits were observed.
Oswestry disability index and visual analog scale (VAS) for pain were outcome measures. Radiological outcomes were vertebral body height and kyphotic angle. Complications included cement leakage, adjacent fractures, and transition to instrumented fusion.
Between June 2015 and December 2016, 96 patients with osteoporotic vertebral fractures who met the inclusion criteria were prospectively enrolled. Preoperative, postoperative, and latest follow-up clinical outcomes were assessed using the Oswestry disability index and VAS. The radiological outcomes included vertebral body height, kyphotic angle, and adjacent fractures. Patients with intractable pain and neurological deficits during the follow-up were indicated for surgical treatment using decompression and instrumented fusion.
Fifty-one patients with osteoporotic compression fractures and 45 with osteoporotic burst fractures were included in this study. Mean follow-up duration was 74 months, and posterior vertebral body height, kyphotic wedge angle, and VAS score were not altered during the follow-up period. Three (5.9%) patients in an osteoporotic compression fracture group and three (6.7%) in a osteoporotic burst fracture group developed persistent pain, further collapse, and neurological deficits, and were indicated for surgical treatment. No significant differences were observed in the rates of adjacent fractures. Percentage of patients who required surgical treatment was not significantly different between the groups.
Osteoporotic burst fractures with asymptomatic spinal canal compromise treated with percutaneous vertebroplasty are safe and effective for pain management during long-term follow-up.
经皮椎体成形术治疗骨质疏松性爆裂骨折仍存在争议。先前的一项研究表明,无症状性椎管受压的骨质疏松性爆裂骨折并非经皮椎体成形术的禁忌证。
为了确定这些结果在长期内是否持续存在,我们在长期内继续观察短期研究中的患者。
前瞻性研究。
骨质疏松性椎体骨折患者被分类为丹尼斯I型和II型以及AO A1-A4型,且未观察到神经功能缺损。
Oswestry功能障碍指数和疼痛视觉模拟量表(VAS)作为观察指标。影像学结果为椎体高度和后凸角。并发症包括骨水泥渗漏、相邻椎体骨折以及转为器械辅助融合术。
在2015年6月至2016年12月期间,前瞻性纳入了96例符合纳入标准的骨质疏松性椎体骨折患者。术前、术后及最新随访时的临床结果采用Oswestry功能障碍指数和VAS进行评估。影像学结果包括椎体高度、后凸角和相邻椎体骨折。随访期间出现顽固性疼痛和神经功能缺损的患者接受减压和器械辅助融合术的手术治疗。
本研究纳入了51例骨质疏松性压缩骨折患者和45例骨质疏松性爆裂骨折患者。平均随访时间为74个月,随访期间椎体后缘高度、后凸楔角和VAS评分未发生改变。骨质疏松性压缩骨折组有3例(5.9%)患者和骨质疏松性爆裂骨折组有3例(6.7%)患者出现持续性疼痛、进一步塌陷和神经功能缺损,并接受了手术治疗。相邻椎体骨折发生率无显著差异。两组间需要手术治疗的患者百分比无显著差异。
经皮椎体成形术治疗无症状性椎管受压的骨质疏松性爆裂骨折在长期随访中对疼痛管理是安全有效的。