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[心血管并发症的严重2019冠状病毒感染背景]

[Severe coronavirus-2 infection background for cardiovascular complications].

作者信息

Cibrian-Delgado Juan Angel, Gutiérrez-Galván Maraí Xóchitl, Urzua-Gonzalez Agustin Ramiro, Huallpa-Rodríguez Sadia, Hernandez-Gonzale Martha A

机构信息

Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No. 1, Departamento de Cardiología. León, Guanajuato, México.

Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No. 1, División de Investigación en Salud. León, Guanajuato, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2024 Mar 4;62(2):1-7. doi: 10.5281/zenodo.10711339.

Abstract

BACKGROUND

Covid-19 infection can affect the cardiovascular system in the long term, due to the inflammation and endothelial damage caused by SARS-CoV-2. It is unknown whether patients who have had severe covid-19 have a higher risk of cardiovascular complications than those who have not.

OBJECTIVE

To compare the presentation of cardiovascular complications in patients with a history of severe SARS-CoV-2 infection and population without this history.

MATERIAL AND METHODS

An observational analytical cohort study was conducted that included 988 patients, with a calculation for the sample size to detect a minimum RR of 1.5 with a statistical power of 80%. The outcome was measured through electronic medical records and variables were compared. A descriptive analysis was performed using measures of central tendency and dispersion for quantitative variables and absolute and relative frequencies for qualitative variables.

RESULTS

The history of severe covid-19 infection is related to a higher risk of rehospitalization for cardiovascular causes. There was an increase in the frequency of endocarditis, arrhythmias and thrombotic events. Type 4a infarcts and thrombi in the right atrium were more common in patients with covid-19.

CONCLUSIONS

Covid-19 was associated with a higher hospital readmission for cardiac problems, such as endocarditis and arrhythmias. A persistent negative impact on long-term cardiovascular health was identified in these patients.

摘要

背景

由于严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的炎症和内皮损伤,新冠病毒19感染可长期影响心血管系统。曾患重症新冠病毒19的患者是否比未患该疾病的患者有更高的心血管并发症风险尚不清楚。

目的

比较有重症SARS-CoV-2感染病史的患者与无此病史人群的心血管并发症表现。

材料与方法

进行了一项观察性分析队列研究,纳入988例患者,计算样本量以检测最小相对危险度为1.5且统计效能为80%。通过电子病历测量结局并比较变量。对定量变量使用集中趋势和离散度测量进行描述性分析,对定性变量使用绝对和相对频率进行描述性分析。

结果

重症新冠病毒19感染病史与因心血管原因再次住院的较高风险相关。心内膜炎、心律失常和血栓形成事件的发生率增加。4a型梗死和右心房血栓在新冠病毒19患者中更常见。

结论

新冠病毒19与因心脏问题(如心内膜炎和心律失常)导致的较高再入院率相关。在这些患者中发现了对长期心血管健康的持续负面影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3914/12129565/24a000747ac6/04435117-62-2-e5667-c001.jpg

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