恶性脑肿瘤囊液中游离腐胺和N1-乙酰亚精胺水平升高。
Elevated levels of free putrescine and N1-acetylspermidine in cyst fluids of malignant brain tumours.
作者信息
Yamazaki H, Tsukahara T, Uki J, Matsuzaki S
出版信息
J Neurol Neurosurg Psychiatry. 1986 Feb;49(2):209-10. doi: 10.1136/jnnp.49.2.209.
The contents of free and conjugated polyamines in cyst fluids of brain tumours were analysed. The putrescine and N1-acetylspermidine levels in cyst fluids of malignant brain tumours were significantly higher than those of benign tumours. The free spermidine levels in malignant and benign tumours were about the same, while the total spermidine levels were higher in malignant than those in benign tumours. These results suggest that polyamine levels in cyst fluids reflect the altered polyamine metabolism in brain tumours.
对脑肿瘤囊液中游离和结合多胺的含量进行了分析。恶性脑肿瘤囊液中的腐胺和N1-乙酰亚精胺水平显著高于良性肿瘤。恶性和良性肿瘤中游离亚精胺水平大致相同，而恶性肿瘤中的总亚精胺水平高于良性肿瘤。这些结果表明，囊液中的多胺水平反映了脑肿瘤中多胺代谢的改变。
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