Hasan Abdulkarim, Alsagheer Khaled Ahmed, Abdelwahab Ali Mohamed Galal, Khatan Ahmed Mohammed, Ali Hassan Mansour Hosny, Whaiba Abdallah
Department of Pathology, Faculty of Medicine, Al-Azhar University, Cairo, EGY.
Department of Laboratory, Al-Baha Health Cluster, Ministry of Health, Al-Baha, SAU.
Cureus. 2024 Oct 6;16(10):e70964. doi: 10.7759/cureus.70964. eCollection 2024 Oct.
Poroma is a relatively rare benign adnexal neoplastic lesion that usually affects elderly patients in the extremities, with an unclear pathogenesis. It is notable for having a variety of morphological appearances that make diagnosis challenging, particularly when observed on an uncommon anatomical site. Here, we present a case of a woman in her mid-50s who presented with a skin pedunculated lesion over the right thigh. The lesion had a smooth surface and clinically mimicked a skin tag. The lesion was surgically excised and sent for histopathology. On microscopic examination, anastomosing cords and broad columns of more or less uniform basaloid cells extending to the dermis with no atypical changes were seen, confirming the diagnosis of eccrine poroma. It is emphasized that poromas should be considered in the clinical and histological differential diagnosis of nonacral skin lesions. Complete excision cures the condition and prevents local recurrence.
汗孔瘤是一种相对罕见的良性附属器肿瘤性病变，通常累及四肢的老年患者，其发病机制尚不清楚。它以具有多种形态表现而著称，这使得诊断具有挑战性，尤其是在不常见的解剖部位观察到时。在此，我们报告一例50多岁女性，其右大腿出现一个带蒂皮肤病变。该病变表面光滑，临床上类似皮赘。病变经手术切除并送去做组织病理学检查。显微镜检查可见相互吻合的条索状和较宽的柱状结构，由大致均匀的基底样细胞延伸至真皮，无非典型改变，确诊为小汗腺汗孔瘤。需要强调的是，在非掌跖部皮肤病变的临床和组织学鉴别诊断中应考虑汗孔瘤。完整切除可治愈该病并防止局部复发。
