Brown R H, Beyerl B D, Iseke R, Lavyne M H
J Neurosurg. 1986 Mar;64(3):494-500. doi: 10.3171/jns.1986.64.3.0494.
Neurogenic pulmonary edema (NPE) occurs in association with central nervous system disease without underlying cardiopulmonary problems. It is characterized by profound pulmonary vascular congestion and a fulminant clinical course. Although several reports document a role for experimental brain-stem lesions in the production of NPE, there have been only two studies in man correlating specific brain-stem lesions with NPE. The authors report a case of NPE occurring in a patient with von Hippel-Lindau disease and a dorsal medullary syrinx with postoperative dorsal medullary edema. The anatomical location of this patient's lesion is reviewed in the context of alternative theories of the pathogenesis of NPE.
神经源性肺水肿（NPE）与中枢神经系统疾病相关，且无潜在心肺问题。其特征为严重的肺血管充血和急性临床病程。尽管有几份报告记录了实验性脑干病变在NPE发生中的作用，但仅有两项关于人类的研究将特定脑干病变与NPE相关联。作者报告了一例NPE病例，该病例发生在一名患有冯·希佩尔-林道病且伴有延髓背侧空洞症及术后延髓背侧水肿的患者身上。结合NPE发病机制的其他理论，对该患者病变的解剖位置进行了回顾。
