Soetedjo Nanny Natalia Mulyani, Agustini Dessy, Permana Hikmat
Division of Endocrinology, Metabolism, and Diabetes, Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Bandung, West Java 45363, Indonesia.
Faculty of Medicine, Universitas Sriwijaya, Palembang, South Sumatra 30114, Indonesia.
Int J Cardiol Heart Vasc. 2024 Oct 23;55:101536. doi: 10.1016/j.ijcha.2024.101536. eCollection 2024 Dec.
The thyroid gland is responsible for metabolism, as well as cardiac function and the peripheral vascular system. Thyroid dysfunctions are associated with an increase in the risk of cardiovascular diseases, including heart failure and coronary heart disease atrial fibrillation, by impairing heart contractility, stroke volume, heart rate, peripheral vascular resistance, and electrical activity. Thyroid dysfunctions also alter several cardiovascular risk factors, such as atherosclerosis, hypertension, and dyslipidemia, as well as causing stroke, which is associated with atrial fibrillation. An antiarrhythmic drug, amiodarone, may also induce both thyrotoxicosis and hypothyroidism, so its use requires serial thyroid function testing. Every CVD patient is recommended to be screened and treated for any possible thyroid dysfunction to reduce the patient's mortality and morbidity.
甲状腺负责新陈代谢，以及心脏功能和外周血管系统。甲状腺功能障碍会损害心脏收缩力、每搏输出量、心率、外周血管阻力和电活动，从而增加心血管疾病的风险，包括心力衰竭、冠心病和心房颤动。甲状腺功能障碍还会改变多种心血管危险因素，如动脉粥样硬化、高血压和血脂异常，以及引发与心房颤动相关的中风。抗心律失常药物胺碘酮也可能诱发甲状腺毒症和甲状腺功能减退，因此使用该药物需要定期进行甲状腺功能检测。建议对每位心血管疾病患者进行筛查，并针对任何可能的甲状腺功能障碍进行治疗，以降低患者的死亡率和发病率。
