Fischer E G, Lorenzo A V, Landis W J, Welch K, Ofori-Kwakye S K, Dorval B, Hodgens K J, Kerr C S
J Neurosurg. 1986 Apr;64(4):650-6. doi: 10.3171/jns.1986.64.4.0650.
The authors report a study of the cerebral vasculature of premature rabbits pertaining to the germinal matrix (GM). A pigmented silicone material (Microfil) was injected into the carotid artery of anesthetized rabbits. Methyl methacrylate vascular casts of a similar group of premature rabbits were examined by scanning electron microscopy. The GM is supplied by arteries from both the basal and convexity surfaces of the brain. Vessels could be identified as arteries or veins by their typical patterns of branching and by the characteristic impressions made on the methyl methacrylate casts by endothelial nuclei. Specific evidence of structural weaknesses in the vasculature, which could be a site of predilection for GM bleeding, was not observed. The similarities in basal ganglia vasculature between premature rabbits and humans justifies using the rabbit model to study vascular aspects of the GM and intraventricular hemorrhage.
作者报告了一项关于早产兔生发基质（GM）脑脉管系统的研究。将一种有色硅酮材料（微显影剂）注入麻醉兔的颈动脉。通过扫描电子显微镜检查了一组类似早产兔的甲基丙烯酸甲酯血管铸型。GM由来自脑基底表面和凸面的动脉供血。根据血管典型的分支模式以及内皮细胞核在甲基丙烯酸甲酯铸型上留下的特征性印记，可以将血管识别为动脉或静脉。未观察到脉管系统结构薄弱的具体证据，而这可能是GM出血的好发部位。早产兔和人类基底节脉管系统的相似性证明了使用兔模型研究GM和脑室内出血的血管方面问题的合理性。
