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中国慢性病前瞻性研究(CKB)10个研究地区中,肺功能测定正常但比值降低与死亡率之间的关联,2004 - 2022年

The Association Between Preserved Ratio Impaired Spirometry and Mortality - 10 CKB Study Areas, China, 2004-2022.

作者信息

Ke Yalei, Zhang Xinyi, Sun Dianjianyi, Pei Pei, Du Huaidong, Chen Yiping, Yang Ling, Yang Xiaoming, Wang Kang, Chen Junshi, Chen Zhengming, Lv Jun, Li Liming, Yu Canqing

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.

Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing, China.

出版信息

China CDC Wkly. 2024 Oct 25;6(43):1120-1125. doi: 10.46234/ccdcw2024.228.

Abstract

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: China has the world's most significant public health and economic burden of chronic respiratory disease. However, the association between preserved ratio impaired spirometry (PRISm) and mortality risk is unknown.

WHAT IS ADDED BY THIS REPORT?: The PRISm group exhibited a 37% higher risk of all-cause mortality than the normal group, and the risks of death from cardiovascular diseases, neoplasms, respiratory diseases, and infectious and parasitic diseases were also increased in PRISm. Moreover, the presence of respiratory symptoms or disease was associated with an increased risk of mortality in PRISm.

WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: It is imperative to enhance public awareness of PRISm and to implement measures to facilitate the regression of PRISm toward normal lung function.

摘要

关于该主题已知的信息有哪些?:中国是全球慢性呼吸道疾病公共卫生和经济负担最为严重的国家。然而,肺量计测定值保留率受损(PRISm)与死亡风险之间的关联尚不清楚。

本报告新增了哪些内容?:PRISm组全因死亡风险比正常组高37%,PRISm组中心血管疾病、肿瘤、呼吸系统疾病以及感染性和寄生虫病的死亡风险也有所增加。此外,PRISm中出现呼吸道症状或疾病与死亡风险增加相关。

对公共卫生实践有何启示?:必须提高公众对PRISm的认识,并采取措施促进PRISm向正常肺功能回归。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab6/11534579/72a7b4f6e677/ccdcw-6-43-1120-1.jpg

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