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口腔黏膜类天疱疮

Oral Mucous Membrane Pemphigoid.

作者信息

Babu Cathy, Tamgadge Sandhya, Vidhale Rutuja Gajanan, Pereira Treville

机构信息

Departments of Oral and Maxillofacial Pathology and Microbiology, D. Y. Patil University School of Dentistry, Navi Mumbai, Maharashtra, India.

Oral and Maxillofacial Pathology and Microbiology, D. Y. Patil University School of Dentistry, Navi Mumbai, Maharashtra, India.

出版信息

J Microsc Ultrastruct. 2022 Aug 4;12(3):162-164. doi: 10.4103/jmau.jmau_44_22. eCollection 2024 Jul-Sep.

DOI:10.4103/jmau.jmau_44_22
PMID:39507639
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11537356/
Abstract

Pemphigoid is a group of rare autoimmune diseases affecting the skin and the mucous membrane in which the autoantibodies are directed against the basement membrane zone target antigens causing subepithelial blistering. Oral health professionals are usually the first to identify as more than 90% of cases show oral lesions initially. A lack of diagnostic criteria can lead to misdiagnosis and delay in treatment. We report a unique case of mucous membrane pemphigoid devoid of ocular or cutaneous involvement.

摘要

类天疱疮是一组罕见的自身免疫性疾病，会影响皮肤和黏膜，其中自身抗体针对基底膜带靶抗原，导致上皮下疱形成。口腔健康专业人员通常是最先识别出该病的，因为超过90%的病例最初会出现口腔病变。缺乏诊断标准可能导致误诊和治疗延误。我们报告了一例独特的黏膜类天疱疮病例，该病例无眼部或皮肤受累。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/11537356/99a87eb60cf2/JMAU-12-162-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/11537356/4cad3a335f7f/JMAU-12-162-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/11537356/cc0325f3c21c/JMAU-12-162-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/11537356/39930fb16567/JMAU-12-162-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/11537356/99a87eb60cf2/JMAU-12-162-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/11537356/4cad3a335f7f/JMAU-12-162-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/11537356/cc0325f3c21c/JMAU-12-162-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/11537356/39930fb16567/JMAU-12-162-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/11537356/99a87eb60cf2/JMAU-12-162-g004.jpg

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Oral Mucous Membrane Pemphigoid.口腔黏膜类天疱疮
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Bullous pemphigoid antigen II (BP180) and its soluble extracellular domains are major autoantigens in mucous membrane pemphigoid: the pathogenic relevance to HLA class II alleles and disease severity.大疱性类天疱疮抗原II（BP180）及其可溶性细胞外结构域是黏膜类天疱疮中的主要自身抗原：与HLA II类等位基因及疾病严重程度的致病相关性。
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本文引用的文献

1
Oral mucous membrane pemphigoid in a group of Thai patients-A 15-year retrospective study.一组泰国患者的口腔黏膜类天疱疮——一项15年的回顾性研究
J Dent Sci. 2022 Apr;17(2):1009-1017. doi: 10.1016/j.jds.2021.11.007. Epub 2021 Nov 24.
2
The Diagnosis and Blistering Mechanisms of Mucous Membrane Pemphigoid.黏膜类天疱疮的诊断和起疱机制。
Front Immunol. 2019 Jan 24;10:34. doi: 10.3389/fimmu.2019.00034. eCollection 2019.
3
Oral mucous membrane pemphigoid - Two case reports with varied clinical presentation.口腔黏膜类天疱疮——两例临床表现各异的病例报告。
J Indian Soc Periodontol. 2016 Nov-Dec;20(6):630-634. doi: 10.4103/jisp.jisp_155_16.
4
Pemphigus.天疱疮。
Nat Rev Dis Primers. 2017 May 11;3:17026. doi: 10.1038/nrdp.2017.26.
5
World Workshop on Oral Medicine VI: a systematic review of the treatment of mucous membrane pemphigoid.第六届世界口腔医学研讨会：黏膜类天疱疮治疗的系统评价
Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Aug;120(2):161-71.e20. doi: 10.1016/j.oooo.2015.01.024. Epub 2015 Mar 11.
6
Mucous membrane pemphigoid.黏膜类天疱疮
Dent Clin North Am. 2013 Oct;57(4):611-30. doi: 10.1016/j.cden.2013.07.003. Epub 2013 Aug 15.
7
The first international consensus on mucous membrane pemphigoid: definition, diagnostic criteria, pathogenic factors, medical treatment, and prognostic indicators.关于黏膜类天疱疮的首个国际共识：定义、诊断标准、致病因素、医学治疗及预后指标。
Arch Dermatol. 2002 Mar;138(3):370-9. doi: 10.1001/archderm.138.3.370.