黏膜类天疱疮
Mucous membrane pemphigoid.
作者信息
Xu Hong-Hui, Werth Victoria P, Parisi Ernesta, Sollecito Thomas P
机构信息
Department of Dermatology, No.1 Hospital of China Medical University, 155 North Nanjing Street, Shenyang 110001, China; Department of Dermatology, Philadelphia VA Medical Center, 3900 Woodland Avenue, Philadelphia, PA 19104, USA.
出版信息
Dent Clin North Am. 2013 Oct;57(4):611-30. doi: 10.1016/j.cden.2013.07.003. Epub 2013 Aug 15.
Abstract
Mucous membrane pemphigoid (MMP) is chronic and frequently associated with exacerbations and remissions of clinical signs and symptoms. Clinicians should use pathologic and immunonologic techniques to help diagnose patients. Multidisciplinary collaboration is often necessary for the diagnosis and proper treatment of MMP. Systemic adjuvant immunosuppressive therapy is necessary for patients with progressive disease. In spite of the advances in available immunosuppressive medications and biologics, scarring is a significant complication in many cases. Surgical intervention is not curable; however, it may be necessary for restoring function and improving quality of life.
摘要
黏膜类天疱疮（MMP）是一种慢性疾病，临床症状常反复出现、加重或缓解。临床医生应运用病理和免疫技术辅助诊断患者。MMP的诊断和恰当治疗通常需要多学科协作。对于病情进展的患者，全身性辅助免疫抑制治疗是必要的。尽管现有的免疫抑制药物和生物制剂有所进展，但在许多病例中，瘢痕形成仍是一个严重的并发症。手术干预无法治愈该病；然而，为恢复功能和改善生活质量，手术干预可能是必要的。
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