Özomay Baykal Gülcan, Kurtuluş Duygu, Ata Serap, Sözeri Betül
Division of Pediatric Rheumatology, Ümraniye Training and Research Hospital, İstanbul, Türkiye.
Department of Physical Medicine and Rehabilitation, Ümraniye Training and Research Hospital, İstanbul, Türkiye.
Arch Rheumatol. 2024 May 10;39(3):384-392. doi: 10.46497/ArchRheumatol.2024.10562. eCollection 2024 Sep.
The study aimed to evaluate the frequency of juvenile fibromyalgia syndrome (JFMS) in patients diagnosed with juvenile idiopathic arthritis (JIA) and familial Mediterranean fever (FMF) with joint symptoms and compare them with a healthy control group.
This retrospective study was conducted with 181 participants between January and April 2023. One hundred twenty-one patients with JIA or FMF diagnoses (71 females, 50 males; mean age: 15.6±2.1 years; range, 12 to 23 years) and 60 healthy individuals (36 females, 24 males; mean age: 14.5±1.6 years; range, 12 to 17 years) were included in the patient group and the control group, respectively. The pain and symptom assessment scale was applied for the JFMS diagnosis, and the output data were analyzed with the widespread pain index and symptom severity scale.
Of the patient group, 57% (n=69) were diagnosed with FMF, and 43% (n=52) were diagnosed with JIA. When the two groups were compared with those diagnosed with JFMS, statistical significance was detected (p<0.05). Thirteen (87%) of those diagnosed with JFMS were female, and two (13%) were male, with a statistically significant difference.
In patients with JIA and FMF who complain of chronic musculoskeletal pain, tiredness, and weakness, JFMS diagnosis should always be considered in the clinical evaluation.
本研究旨在评估诊断为青少年特发性关节炎（JIA）和伴有关节症状的家族性地中海热（FMF）的患者中青少年纤维肌痛综合征（JFMS）的发生率，并将其与健康对照组进行比较。
本回顾性研究于2023年1月至4月对181名参与者进行。患者组和对照组分别纳入121例诊断为JIA或FMF的患者（71名女性，50名男性；平均年龄：15.6±2.1岁；范围12至23岁）和60名健康个体（36名女性，24名男性；平均年龄：14.5±1.6岁；范围12至17岁）。采用疼痛和症状评估量表进行JFMS诊断，并使用广泛疼痛指数和症状严重程度量表对输出数据进行分析。
患者组中，57%（n = 69）被诊断为FMF，43%（n = 52）被诊断为JIA。将两组与诊断为JFMS的患者进行比较时，发现有统计学意义（p<0.05）。诊断为JFMS的患者中，13例（87%）为女性，2例（13%）为男性，差异有统计学意义。
对于主诉慢性肌肉骨骼疼痛、疲倦和虚弱的JIA和FMF患者，临床评估时应始终考虑JFMS的诊断。
