Yunus Muhammad B
Section of Rheumatology, Department of Medicine, University of Illinois College of Medicine at Peoria, One Illini Drive, Peoria, IL 61605, USA.
Pain Res Treat. 2012;2012:584573. doi: 10.1155/2012/584573. Epub 2011 Nov 17.
Central sensitivity syndromes (CSS) include fibromyalgia syndrome (FMS), irritable bowel syndrome, temporomandibular disorder, restless legs syndrome, chronic fatigue syndrome, and other similar chronic painful conditions that are based on central sensitization (CS). CSS are mutually associated. In this paper, prevalence of FMS among other members of CSS has been described. An important recent recognition is an increased prevalence of FMS in other chronic pain conditions with structural pathology, for example, rheumatoid arthritis, systemic lupus, ankylosing spondylitis, osteoarthritis, diabetes mellitus, and inflammatory bowel disease. Diagnosis and proper management of FMS among these diseases are of crucial importance so that unwarranted use of such medications as corticosteroids can be avoided, since FMS often occurs when RA or SLE is relatively mild.
中枢敏化综合征（CSS）包括纤维肌痛综合征（FMS）、肠易激综合征、颞下颌关节紊乱症、不安腿综合征、慢性疲劳综合征以及其他基于中枢敏化（CS）的类似慢性疼痛病症。CSS相互关联。本文描述了FMS在CSS其他成员中的患病率。最近一项重要的认识是，FMS在伴有结构病理学改变的其他慢性疼痛病症中患病率增加，例如类风湿性关节炎、系统性红斑狼疮、强直性脊柱炎、骨关节炎、糖尿病和炎症性肠病。在这些疾病中对FMS进行诊断和妥善管理至关重要，这样可以避免不必要地使用皮质类固醇等药物，因为FMS常发生在类风湿性关节炎或系统性红斑狼疮相对较轻的时候。
