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The Best Things Happen When You Least Expect Them: Responsive Neurostimulation During Low-Risk Brain States is Associated with Improved Long-Term Seizure Suppression.当你最不经意时，最美好的事情就会发生：低风险脑状态下的反应性神经刺激与长期癫痫发作抑制改善有关。
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本文引用的文献

1
Closed-loop stimulation in periods with less epileptiform activity drives improved epilepsy outcomes.在癫痫样活动较少的时期进行闭环刺激可改善癫痫治疗效果。
Brain. 2024 Feb 1;147(2):521-531. doi: 10.1093/brain/awad343.
2
Anterior nucleus of the thalamus deep brain stimulation vs temporal lobe responsive neurostimulation for temporal lobe epilepsy.丘脑前核深部脑刺激与颞叶反应性神经刺激治疗颞叶癫痫的比较。
Epilepsia. 2022 Sep;63(9):2290-2300. doi: 10.1111/epi.17331. Epub 2022 Jul 5.
3
Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy.长期脑网络重组预测局灶性癫痫的反应性神经刺激治疗效果。
Sci Transl Med. 2021 Aug 25;13(608). doi: 10.1126/scitranslmed.abf6588.
4
Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy.脑反应性神经刺激治疗局灶性癫痫的 9 年疗效和安全性前瞻性研究。
Neurology. 2020 Sep 1;95(9):e1244-e1256. doi: 10.1212/WNL.0000000000010154. Epub 2020 Jul 20.
5
Responsive cortical stimulation for the treatment of medically intractable partial epilepsy.反应性皮质刺激治疗药物难治性部分性癫痫。
Neurology. 2011 Sep 27;77(13):1295-304. doi: 10.1212/WNL.0b013e3182302056. Epub 2011 Sep 14.
6
Effect of an external responsive neurostimulator on seizures and electrographic discharges during subdural electrode monitoring.硬膜下电极监测期间外部响应性神经刺激器对癫痫发作和脑电图放电的影响。
Epilepsia. 2004 Dec;45(12):1560-7. doi: 10.1111/j.0013-9580.2004.26104.x.
7
Early identification of refractory epilepsy.难治性癫痫的早期识别。
N Engl J Med. 2000 Feb 3;342(5):314-9. doi: 10.1056/NEJM200002033420503.

The Best Things Happen When You Least Expect Them: Responsive Neurostimulation During Low-Risk Brain States is Associated with Improved Long-Term Seizure Suppression.

作者信息

Philipsberg Paul A, Shuman Tristan

机构信息

Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai.

出版信息

Epilepsy Curr. 2024 Jun 14;24(5):350-352. doi: 10.1177/15357597241258287. eCollection 2024 Sep-Oct.

DOI:10.1177/15357597241258287
PMID:39508007
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11536420/
Abstract
摘要