Spadaro J A, Mino D E, Chase S E, Werner F W, Murray D G
J Orthop Res. 1986;4(1):37-44. doi: 10.1002/jor.1100040105.
Previous experiments have suggested that mechanical activity of electrode implants may contribute to the observed bone formation that has been attributed to the electrical currents. This was tested by implanting movable and stationary wires in the medullary canal of the rabbit femora or tibiae. The moving implants uniformly showed significant medullary bone formation at the wire, whereas the stationary ones did not. This bone persisted for as long as 8 weeks and was mostly resorbed by 12 weeks as the implants became fixed. The new trabecular bone closely resembled that typically seen at electrically active implants. Implant motion may have a more important role in electrically induced osteogenesis than previously thought.
先前的实验表明，电极植入物的机械活动可能有助于观察到的归因于电流的骨形成。通过将可移动和固定的金属丝植入兔股骨或胫骨的髓腔内对此进行了测试。可移动的植入物在金属丝处均显示出明显的髓内骨形成，而固定的植入物则没有。这种骨持续长达8周，随着植入物固定，到12周时大部分被吸收。新形成的小梁骨与电活性植入物处通常所见的骨非常相似。植入物的运动在电诱导成骨中可能比以前认为的具有更重要的作用。
