Department of Animal Pathology, University of Zaragoza, Zaragoza, Spain.
Clinical Immunology Laboratory, University of Zaragoza, Zaragoza, Spain.
Vet Q. 2024 Dec;44(1):1-8. doi: 10.1080/01652176.2024.2421308. Epub 2024 Nov 7.
is a major vector of in the Mediterranean. While the seroprevalence of leishmaniosis in Spanish dogs and cats has been studied, data on the exposure of cats to bites under natural conditions without repellents is limited. Stray cats could serve as sentinels for and exposure. This study analyzed sera from 204 apparently healthy stray cats, collected from January 2021 to January 2022, for antibodies against saliva and parasites. Anti-sand fly antibodies were detected in 40.69% of cats using an ELISA with the recombinant salivary protein SP03B of . Seroprevalence of infection was 23.52% by Western blot and 27.41% by ELISA, with an overall seroprevalence of 40.69% (95% CI 34.18-47.54%). This is the first assessment of antibody response to saliva and in naturally exposed stray cats in Spain. Further research is needed to examine the salivary antigens recognized by cats and to explore the relationship between exposure and infection severity in cats.
是地中海地区的 重要传播媒介。尽管已经研究了西班牙犬猫利什曼病的血清流行率，但在没有驱虫剂的情况下，关于猫在自然条件下接触 叮咬的暴露数据有限。流浪猫可能是 和 的哨兵。本研究分析了 204 只来自 2021 年 1 月至 2022 年 1 月的明显健康流浪猫的血清，以检测针对 的唾液和 寄生虫的抗体。使用重组蛋白 SP03B 的 ELISA 检测到 40.69%的猫具有抗 苍蝇抗体。Western blot 检测到 感染的血清阳性率为 23.52%，ELISA 检测为 27.41%，总血清阳性率为 40.69%（95%CI 34.18-47.54%）。这是首次评估西班牙自然暴露的流浪猫对 唾液和 的抗体反应。需要进一步研究来检查猫识别的唾液抗原，并探索 暴露与猫 感染严重程度之间的关系。
