Grove Jeremy L, Tunno Angela M, Cheek Shayna M, Weller Bridget E, Heilbron Nicole C, Inscoe Adrienne B, Payne B Keith, Tyndal Tia L, Goldston David B
Department of Psychiatry & Behavioral Sciences, Duke University, Durham, North Carolina, USA.
Wayne State University School of Social Work, Detroit, Michigan, USA.
Suicide Life Threat Behav. 2025 Apr;55(2):e13140. doi: 10.1111/sltb.13140. Epub 2024 Nov 7.
Individuals who are depressed, have suicide attempts, and a substance use disorder (SUD) may have different patterns of suicidal thoughts and behaviors and respond differently to cues associated with suicide and death.
Implicit affective reactions to visual cues suggestive of suicide and death (as well as to pleasant, unpleasant, and neutral cues), were compared among three groups of hospitalized adults: (a) depressed patients without the histories of suicidal behavior (depression only), (b) depressed patients with suicide attempts, but no current substance abuse disorder (SA), and (c) depressed patients with both suicide attempts and substance use disorder (SA + SUD).
The SA group demonstrated higher positive evaluations of visual cues associated with suicide and death when compared to the SA + SUD group. The SA + SUD group demonstrated the lowest positive evaluation of suicide-related stimuli as well as less positive evaluation of visual cues of generally unpleasant stimuli.
Differences observed between SA and SA + SUD participants underscore differences in responses to cues related to suicide, which may reflect differences in mechanisms of risk.
患有抑郁症、有自杀未遂经历且患有物质使用障碍(SUD)的个体可能具有不同的自杀思维和行为模式,并且对与自杀和死亡相关的线索反应不同。
比较了三组住院成年人对暗示自杀和死亡的视觉线索(以及愉快、不愉快和中性线索)的内隐情感反应:(a)无自杀行为史的抑郁症患者(仅抑郁症),(b)有自杀未遂经历但目前无物质滥用障碍(SA)的抑郁症患者,以及(c)有自杀未遂经历且患有物质使用障碍的抑郁症患者(SA + SUD)。
与SA + SUD组相比,SA组对与自杀和死亡相关的视觉线索表现出更高的积极评价。SA + SUD组对与自杀相关的刺激表现出最低的积极评价,对一般不愉快刺激的视觉线索的积极评价也较低。
SA组和SA + SUD组参与者之间观察到的差异强调了对与自杀相关线索反应的差异,这可能反映了风险机制的差异。