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与HELLP综合征相关的血液学异常在产前逆转。三例报告。

Antepartum reversal of hematologic abnormalities associated with the HELLP syndrome. A report of three cases.

作者信息

Clark S L, Phelan J R, Allen S H, Golde S R

出版信息

J Reprod Med. 1986 Jan;31(1):70-2.

PMID:3950889
Abstract

The "HELLP syndrome" refers to the occurrence of thrombocytopenia, elevated liver enzymes and, at times, hemolysis in patients with preeclampsia. Although uncontrolled series have reported a reversal of thrombocytopenia and elevated liver enzymes with aspirin and colloid infusion, most authors recommend that delivery be done soon after the diagnosis is made. The abnormal laboratory parameters of the HELLP syndrome may be reversed completely with bed rest alone, and with preterm gestations, conservative management may be possible.

摘要

“HELLP综合征”指的是先兆子痫患者出现血小板减少、肝酶升高,有时还伴有溶血。尽管非对照系列研究报告称,阿司匹林和胶体输注可使血小板减少和肝酶升高得到缓解,但大多数作者建议在确诊后尽快分娩。HELLP综合征异常的实验室指标可能仅通过卧床休息就完全恢复正常,对于早产情况,保守治疗或许可行。

相似文献

1
Antepartum reversal of hematologic abnormalities associated with the HELLP syndrome. A report of three cases.与HELLP综合征相关的血液学异常在产前逆转。三例报告。
J Reprod Med. 1986 Jan;31(1):70-2.
2
Preeclampsia/eclampsia with hemolysis, elevated liver enzymes, and thrombocytopenia.伴有溶血、肝酶升高和血小板减少的子痫前期/子痫
Obstet Gynecol. 1985 Nov;66(5):657-60.
3
[Disorders of liver function, thrombopenia and hemolysis in a special clinical form of hypertension in pregnancy (the so-called HELLP syndrome)].[妊娠高血压特殊临床形式中的肝功能障碍、血小板减少和溶血(所谓的HELLP综合征)]
Geburtshilfe Frauenheilkd. 1988 Sep;48(9):637-40. doi: 10.1055/s-2008-1026555.
4
HELLP syndrome.HELLP综合征。
Ann Chir Gynaecol Suppl. 1987;202:26-8.
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[Follow-up in HELLP syndrome].[HELLP综合征的随访]
Zentralbl Gynakol. 1990;112(5):273-7.
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[HELLP syndrome: a rare, threatening complication in pre-eclampsia].[HELLP综合征:子痫前期一种罕见且危险的并发症]
Geburtshilfe Frauenheilkd. 1986 Sep;46(9):637-9. doi: 10.1055/s-2008-1036270.
7
Thrombocytopenia with the HELLP syndrome. Report of two cases with reversal in normotensive and nonproteinuric gravidas.血小板减少症合并HELLP综合征。两例血压正常且无蛋白尿孕妇病情逆转的报告。
J Reprod Med. 1998 Mar;43(3):227-9.
8
Imitators of severe preeclampsia.重度子痫前期的模仿者
Obstet Gynecol. 2007 Apr;109(4):956-66. doi: 10.1097/01.AOG.0000258281.22296.de.
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Factors that influence morbidity and mortality in severe preeclampsia, eclampsia and hemolysis, elevated liver enzymes, and low platelet count syndrome.影响重度子痫前期、子痫及溶血、肝酶升高和血小板减少综合征发病率及死亡率的因素。
Saudi Med J. 2006 Jul;27(7):1015-8.
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[Importance of thrombocytopenia for the management of HELLP syndrome: a report of 104 cases].
J Gynecol Obstet Biol Reprod (Paris). 2003 Oct;32(6):541-8.

引用本文的文献

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Corticosteroids for HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome in pregnancy.妊娠期HELLP(溶血、肝酶升高、血小板减少)综合征的糖皮质激素治疗
Cochrane Database Syst Rev. 2010 Sep 8(9):CD008148. doi: 10.1002/14651858.CD008148.pub2.
2
Hemolysis, elevated liver enzymes, and low platelets in pregnancy (HELLP syndrome). A case report and literature review.
Dig Dis Sci. 1991 Nov;36(11):1649-52. doi: 10.1007/BF01296411.
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Pathogenesis of Purtscher's retinopathy. An experimental study.普尔夏视网膜病变的发病机制。一项实验研究。
Graefes Arch Clin Exp Ophthalmol. 1992;230(3):286-91. doi: 10.1007/BF00176306.