Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria, Australia.
Aberdeen Centre for Women's Health Research, University of Aberdeen, Aberdeen, United Kingdom.
PLoS One. 2024 Nov 7;19(11):e0310560. doi: 10.1371/journal.pone.0310560. eCollection 2024.
To investigate pregnant women's preferences for risks of vaginal and caesarean birth, including possible impacts on future fertility.
In this discrete choice experiment, low-risk nulliparous pregnant women recruited after 28 weeks of gestation evaluated eight choice sets, each between two different hypothetical births scenarios which intermixed the risks of planned caesarean or vaginal birth. Scenarios consisted of six attributes: pain, maternal health, neonatal health, risk of unplanned intervention, impact on fertility and risk of complications in the next pregnancy. All scenarios contained risks to neonatal health as neither vaginal nor caesarean birth guarantee an ideal outcome. Choice data were analysed using a conditional logistic regression model.
Between June and September 2023, 211 participants, including 34 from pilot interviews, completed the questionnaire. Influential attributes were maternal health (conditional odds ratio [COR] 1.29, 95% CI 1.17 to 1.42, p<0.001) and risk of unplanned intervention (COR 1.37, 95% CI 1.24 to 1.51, p<0.001), favouring caesarean birth. Conversely, impact on fertility (COR 0.75, 95% CI 0.68 to 0.83, p<0.001) and complications in the next pregnancy favoured vaginal birth (COR 0.90, 95% CI 0.82 to 1.00, p = 0.045).
Participants weighed the included morbidity risks of planned caesarean and vaginal birth in a low-risk pregnancy approximately equally. To facilitate an informed birth decision, clinicians should, apart from neonatal outcomes, particularly consider discussing impacts on fertility, maternal health and the risks of unplanned intervention or future pregnancy complications.
调查孕妇对阴道分娩和剖宫产风险的偏好,包括对未来生育能力的可能影响。
在这项离散选择实验中,招募了 28 周妊娠后的低风险初产妇,让她们评估 8 个选择集,每个选择集在两种不同的假设分娩情景之间进行混合,这两种情景混合了计划剖宫产或阴道分娩的风险。情景由 6 个属性组成:疼痛、产妇健康、新生儿健康、意外干预的风险、对生育能力的影响以及下一次妊娠并发症的风险。所有情景都包含新生儿健康风险,因为阴道分娩和剖宫产都不能保证理想的结果。使用条件逻辑回归模型分析选择数据。
在 2023 年 6 月至 9 月期间,211 名参与者(包括 34 名来自试点访谈的参与者)完成了问卷。有影响力的属性是产妇健康(条件比值比[COR]1.29,95%可信区间 1.17 至 1.42,p<0.001)和意外干预的风险(COR 1.37,95%可信区间 1.24 至 1.51,p<0.001),有利于剖宫产。相反,对生育能力的影响(COR 0.75,95%可信区间 0.68 至 0.83,p<0.001)和下一次妊娠并发症(COR 0.90,95%可信区间 0.82 至 1.00,p=0.045)有利于阴道分娩。
在低风险妊娠中,参与者对计划剖宫产和阴道分娩的包括发病率在内的风险进行了大致平衡的权衡。为了促进知情分娩决策,临床医生除了新生儿结局外,还应特别讨论对生育能力、产妇健康以及意外干预或未来妊娠并发症风险的影响。