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[标准方法治疗泌乳素分泌型垂体癌的疗效]

[Efficacy of standard methods in the treatment of prolactin-secreting pituitary carcinoma].

作者信息

Astafyeva L I, Kalinin P L, Trunin Y Y, Kobyakov G L, Sidneva Y G

机构信息

Burdenko Neurosurgery Center.

出版信息

Probl Endokrinol (Mosk). 2024 Nov 5;70(5):40-45. doi: 10.14341/probl13401.

Abstract

Pituitary carcinoma (metastatic neuroendocrine tumor of the pituitary gland) is the pituitary tumor with confirmed craniospinal and/or systemic metastases. These tumors are extremely rare accounting for only 0.1% to 0.5% of all pituitary tumours and are characterized by high mortality. In the presented case, pituitary carcinoma with intracranial metastasis was diagnosed in a young patient 25 years after manifestation of an aggressive recurrent prolactin-secreting pituitary tumor. Standard therapy (removal of metastasis, radiation therapy, cabergoline therapy) resulted in a long-term remission of the disease.

摘要

垂体癌(垂体转移性神经内分泌肿瘤)是一种已证实发生颅脊髓和/或全身转移的垂体肿瘤。这些肿瘤极其罕见,仅占所有垂体肿瘤的0.1%至0.5%,且具有高死亡率的特点。在本病例中,一名年轻患者在侵袭性复发性泌乳素分泌型垂体肿瘤出现25年后被诊断为颅内转移的垂体癌。标准治疗(转移灶切除、放射治疗、卡麦角林治疗)使疾病长期缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5725/11610635/940eaa6c3cc5/problendo-70-13401-g001.jpg

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