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紫外线光功能化对种植体周围生物膜形成的预防作用:一项随机研究。

Preventive Effect of Ultraviolet Photofunctionalization on Peri-implant Biofilm Formation: An Randomized Study.

作者信息

Goel Akanksha, Swami Vinit, Patil Amol Somaji, Swami Vasanthi Vinit

机构信息

Department of Dental Surgery, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India.

Department of Orthodontics and Dentofacial Orthopedics, Bharati Vidyapeeth Dental College and Hospital, Deemed to be University, Pune, Maharashtra, India.

出版信息

Contemp Clin Dent. 2024 Jul-Sep;15(3):192-197. doi: 10.4103/ccd.ccd_106_24. Epub 2024 Sep 25.

DOI:10.4103/ccd.ccd_106_24
PMID:39512295
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11540206/
Abstract

BACKGROUND

Peri-implant biofilm formation due to local bacterial colonization is one of the important factors for the instability of temporary anchorage devices (TADs).

AIM

The aim of this study was to quantify and compare the colonization of on ultraviolet (UV) treated and untreated titanium TADs.

MATERIALS AND METHODS

This prospective, study included 20 subjects requiring orthodontic treatment with first premolar extraction, followed by retraction of the anterior teeth with absolute anchorage using TADs. TADs were placed interdentally, in the keratinized tissue between the upper second premolar and the first molar on the buccal side, at the mucogingival junction. It was a split-mouth study where one side of TAD was UV-treated for 15 min, and the other side was kept untreated as a control. TADs were removed after 6 months for quantification on both sides and were compared for biofilm reduction.

STATISTICAL ANALYSIS

Statistical software was used to perform unpaired -tests for the individual samples as well as for comparing total UV-treated and untreated samples. <0.05 was considered significant.

RESULTS

The mean bacterial count (per ml) was found to be 2.2 × 10 copy numbers and 8.9 × 10 copy numbers in the UV group and untreated group, respectively. The total count of bacteria was found to be less in the UV-treated group compared to the untreated group.

CONCLUSIONS

The study concludes that UV photofunctionalization results in a significant reduction of colony on TADs with reduced chances of failure due to inflammation.

摘要

背景

局部细菌定植导致种植体周围生物膜形成是临时锚固装置(TADs)不稳定的重要因素之一。

目的

本研究的目的是量化和比较紫外线(UV)处理和未处理的钛制TADs上的细菌定植情况。

材料与方法

这项前瞻性[此处原文缺失具体研究类型]研究纳入了20名需要拔除第一前磨牙进行正畸治疗,随后使用TADs进行绝对支抗内收前牙的受试者。TADs放置在牙间隙,位于上颌第二前磨牙和第一磨牙颊侧角化组织的龈黏膜交界处。这是一项双侧对照研究,一侧的TAD接受15分钟的紫外线处理,另一侧作为对照未进行处理。6个月后取出TADs,对两侧进行细菌定量,并比较生物膜减少情况。

统计分析

使用统计软件对单个样本以及比较紫外线处理组和未处理组的总体样本进行非配对[此处原文缺失具体检验类型]检验。P<0.05被认为具有统计学意义。

结果

紫外线处理组和未处理组的平均细菌计数(每毫升)分别为2.2×10[此处原文缺失具体指数]拷贝数和8.9×10[此处原文缺失具体指数]拷贝数。与未处理组相比,紫外线处理组的细菌总数较少。

结论

该研究得出结论,紫外线光功能化可显著减少TADs上的细菌菌落,降低因炎症导致失败的几率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ea/11540206/d4b0a42505f2/CCD-15-192-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ea/11540206/2a27844792f8/CCD-15-192-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ea/11540206/d4b0a42505f2/CCD-15-192-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ea/11540206/2a27844792f8/CCD-15-192-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ea/11540206/d4b0a42505f2/CCD-15-192-g002.jpg

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本文引用的文献

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Matrix Metalloproteinase-8 Levels in Peri-Miniscrew Crevicular Fluid During Immediate and Delayed Orthodontic Loading--A Split-Mouth Study.即刻与延迟正畸加载过程中微型种植体周围龈沟液中基质金属蛋白酶-8水平——一项双侧对照研究
Int J Oral Maxillofac Implants. 2023 Jan-Feb;38(1):130-135. doi: 10.11607/jomi.9705.
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Clinical Applications of Photofunctionalization on Dental Implant Surfaces: A Narrative Review.光功能化在牙种植体表面的临床应用:一项叙述性综述。
J Clin Med. 2022 Sep 30;11(19):5823. doi: 10.3390/jcm11195823.
3
Bone-Miniscrew Contact and Surface Element Deposition on Orthodontic Miniscrews After Ultraviolet Photofunctionalization.
经紫外线光功能化处理后正畸微螺钉表面元素沉积与骨-微螺钉接触情况
Int J Oral Maxillofac Implants. 2020 Nov/Dec;35(6):1090-1097. doi: 10.11607/jomi.8391.
4
UV-photofunctionalization of a biomimetic coating for dental implants application.用于牙种植体应用的仿生涂层的 UV 光功能化。
Mater Sci Eng C Mater Biol Appl. 2020 May;110:110657. doi: 10.1016/j.msec.2020.110657. Epub 2020 Jan 25.
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Streptococcus sanguinis biofilm formation & interaction with oral pathogens.血链球菌生物膜形成及与口腔病原菌的相互作用。
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J Biomed Mater Res B Appl Biomater. 2018 Aug;106(6):2284-2294. doi: 10.1002/jbm.b.34033. Epub 2017 Nov 3.
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Efficacy of Second Molar to Achieve Anchorage Control in Maximum Anchorage Cases.第二磨牙在强支抗病例中实现支抗控制的疗效。
Med J Armed Forces India. 2010 Jul;66(3):220-4. doi: 10.1016/S0377-1237(10)80041-3. Epub 2011 Jul 21.
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Photofunctionalization of Dental Implants.牙种植体的光功能化
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9
Effect of UV-photofunctionalization on oral bacterial attachment and biofilm formation to titanium implant material.紫外线光功能化对口腔细菌在钛种植材料上的附着及生物膜形成的影响。
Biomaterials. 2015 Oct;67:84-92. doi: 10.1016/j.biomaterials.2015.07.030. Epub 2015 Jul 17.
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