Division of Nutrition, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Pathology, WenZhou Medical University Affiliated Taizhou Hospital, Taizhou, Zhejiang, China.
BMJ Open. 2024 Nov 9;14(11):e086703. doi: 10.1136/bmjopen-2024-086703.
The present study aimed to evaluate whether body mass index (BMI) and body fat percentage (BFP) could be used to predict pregnancy outcomes in patients with gestational diabetes mellitus (GDM).
Retrospective cohort study.
Wenzhou Medical University Affiliated Second Hospital (Zhejiang Province, China). Clinical data were collected from electronic medical records.
Data from 683 patients with GDM admitted to the Wenzhou Medical University Affiliated Second Hospital between January 2019 and December 2021 were retrospectively analysed.
Pregnancy outcomes.
The results showed that pregnant women with BFP ≥33% were more prone to abnormal amniotic fluid volume, abnormal blood pressure and anaemia (p<0.05). Additionally, these patients were more likely to experience postpartum haemorrhage and macrosomia, as well as risk factors associated with caesarean section at labour (p<0.05). BMI exhibited a strong predictive value for abnormal blood pressure (OR 1.170; 95% CI 1.090 to 1.275), anaemia (OR 1.073; 95% CI 1.016 to 1.134), caesarean section (OR 1.150; 95% CI 1.096 to 1.208) and macrosomia (OR 1.169; 95% CI 1.063 to 1.285). Additionally, classified BFP had a predictive value for abnormal amniotic fluid volume (OR 3.196; 95% CI 1.294 to 7.894), abnormal blood pressure (OR 2.321; 95% CI 1.186 to 4.545), anaemia (OR 1.817; 95% CI 1.216 to 2.714), and caesarean section (OR 1.734; 95% CI 1.270 to 2.367).
The results suggest that patients with GDM with BFP ≥33% were more likely to experience unfavourable pregnancy outcomes, undergo caesarean section and develop macrosomia. The combination of BMI with classified BFP could better predict abnormal blood pressure and caesarean section in patients with GDM during the middle and late stages of pregnancy.
本研究旨在评估体重指数（BMI）和体脂百分比（BFP）是否可用于预测妊娠期糖尿病（GDM）患者的妊娠结局。
回顾性队列研究。
温州医科大学附属第二医院（中国浙江省）。临床数据来自电子病历。
回顾性分析 2019 年 1 月至 2021 年 12 月期间在温州医科大学附属第二医院就诊的 683 例 GDM 患者的数据。
妊娠结局。
结果显示，BFP≥33%的孕妇更容易出现羊水异常、血压异常和贫血（p<0.05）。此外，这些患者更易发生产后出血和巨大儿，以及与分娩时剖宫产相关的危险因素（p<0.05）。BMI 对血压异常（OR 1.170；95%CI 1.090 至 1.275）、贫血（OR 1.073；95%CI 1.016 至 1.134）、剖宫产（OR 1.150；95%CI 1.096 至 1.208）和巨大儿（OR 1.169；95%CI 1.063 至 1.285）具有较强的预测价值。此外，分类 BFP 对羊水异常（OR 3.196；95%CI 1.294 至 7.894）、血压异常（OR 2.321；95%CI 1.186 至 4.545）、贫血（OR 1.817；95%CI 1.216 至 2.714）和剖宫产（OR 1.734；95%CI 1.270 至 2.367）有预测价值。
研究结果表明，BFP≥33%的 GDM 患者更易出现不良妊娠结局、行剖宫产术和发生巨大儿。BMI 联合分类 BFP 可更好地预测中晚期 GDM 患者的血压异常和剖宫产。
