Washington University, St. Louis, USA.
University of Rochester, USA.
Sleep Med. 2022 Jun;94:54-62. doi: 10.1016/j.sleep.2022.04.002. Epub 2022 Apr 14.
To compare sleep behavior before and during pregnancy.
In this prospective cohort study, healthy women were followed from pre-pregnancy until delivery. At pre-pregnancy and each trimester, participants completed validated questionnaires of chronotype and sleep quality and timing, including the Munich ChronoType Questionnaire, Epworth Sleepiness Scale, and Pittsburgh Sleep Quality Index. The primary outcomes were sleep period start and end times, sleep duration, sleep midpoint, and social jetlag, compared between pre-pregnancy and each trimester. Wrist actigraphy was used to measure the same outcomes in a subset of participants.
Eighty-six women were included in analysis of questionnaires. Of these, 37 provided complete actigraphy data. Questionnaire and actigraphy data indicate that participants had less social jetlag during pregnancy than before pregnancy. Sleep period start times were earlier on both work and free days in the first and second trimesters than pre-pregnancy, and returned to pre-pregnancy times by the third trimester. Actigraphy data revealed that, compared to pre-pregnancy, participants had longer sleep periods in all trimesters on work days and in the first trimester on free days. Sleep surveys revealed that participants had poorer sleep quality in the first and third trimesters and more sleepiness in the first trimester than pre-pregnancy.
The first trimester of pregnancy is characterized by earlier sleep period start time, longer sleep duration, and poorer sleep quality than pre-pregnancy. Sleep quality temporarily improves in the second trimester, and sleep period start time returns to pre-pregnancy time by the third trimester.
Multiple parameters of sleep have been studied in the context of pregnancy and pregnancy outcomes, but rarely in comparison to pre-pregnancy or longitudinally through pregnancy.
Actigraphy and questionnaire data reveal sleep timing and quality change throughout pregnancy. These data on sleep changes in healthy pregnancy can be used as a baseline to identify sleep-related risk factors throughout pregnancy.
比较妊娠前后的睡眠行为。
在这项前瞻性队列研究中，健康女性从孕前一直随访到分娩。在孕前和每个孕期，参与者都完成了经过验证的睡眠时相和睡眠质量及时间的问卷，包括慕尼黑时型问卷、Epworth 嗜睡量表和匹兹堡睡眠质量指数。主要结局指标是与孕前相比，每个孕期的睡眠起始和结束时间、睡眠时间、睡眠中点和社会时差。在部分参与者中，使用腕动仪来测量相同的结果。
86 名女性纳入问卷分析。其中 37 名提供了完整的腕动仪数据。问卷和腕动仪数据表明，与孕前相比，孕妇在孕期的社会时差较小。在第一和第二孕期，工作和休息日的睡眠起始时间均早于孕前，第三孕期则恢复到孕前时间。腕动仪数据显示，与孕前相比，所有孕期工作日的睡眠时间延长，第一孕期的休息日睡眠时间也延长。睡眠调查显示，与孕前相比，孕妇在第一和第三孕期的睡眠质量较差，在第一孕期的嗜睡程度较高。
与孕前相比，妊娠第一孕期的睡眠起始时间较早、睡眠时间较长、睡眠质量较差。第二孕期睡眠质量暂时改善，第三孕期睡眠起始时间恢复到孕前水平。
多项与妊娠和妊娠结局相关的睡眠参数已得到研究，但很少有研究将其与孕前或整个孕期进行比较。
腕动仪和问卷数据揭示了整个孕期的睡眠时相和睡眠质量变化。这些关于健康妊娠期间睡眠变化的数据可作为整个孕期识别与睡眠相关的风险因素的基线。
