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小鼠肛门与生殖器间距数据的表达。

The expression of ano-genital distance data in the mouse.

作者信息

Graham S, Gandelman R

出版信息

Physiol Behav. 1986 Jan;36(1):103-4. doi: 10.1016/0031-9384(86)90081-8.

DOI:10.1016/0031-9384(86)90081-8
PMID:3952167
Abstract

Ano-genital distance (AGD) obtained from male and female mice at birth correlated significantly with body weight. Body length did not correlate significantly with AGD in females. Although it did so in the males, the coefficient accounted for less than half of the variance relative to that obtained by correlating AGD with weight. It is suggested that transformed AGD scores (AGD/body weight) rather than raw AGD data be analyzed when AGD is used to determine whether an independent variable that may affect body weight influences the prenatal hormone milieu.

摘要

出生时从雄性和雌性小鼠获得的肛门生殖器距离(AGD)与体重显著相关。雌性小鼠的体长与AGD无显著相关性。虽然雄性小鼠有相关性,但相对于将AGD与体重相关联所获得的方差而言,该系数占比不到一半。当使用AGD来确定可能影响体重的自变量是否影响产前激素环境时,建议分析转换后的AGD分数(AGD/体重)而非原始AGD数据。

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