Service de Médecine intensive et réanimation, CHU Clermont-Ferrand, Clermont-Ferrand, France.
Service de Nutrition, CHU Clermont-Ferrand, Clermont-Ferrand, France.
Sci Rep. 2024 Nov 9;14(1):27389. doi: 10.1038/s41598-024-78686-8.
To determine the prevalence of functional, respiratory and renal impairments and of post-intensive-care-syndrome (PICS) among patients who had attended a post-ICU multidisciplinary consultation (post-ICU-MC) around 3 months after ICU discharge, we performed a retrospective, monocentric observational study, at Clermont Ferrand University hospital, France. We included patients who had attended a post-ICU-MC. Their characteristics during ICU stay and at the post-ICU-MC were collected. Functional status was assessed by the 6-min-walking test, handgrip test and peak inspiratory pressure, respiratory function by exploratory functional outcomes, mental status by SF-36 score, and quality of life by SF-36 score and European Quality of Life 5 Dimensions questionnaire. Overall, we enrolled 67 patients, of whom 70%, 74%, and 68% had functional, respiratory, and renal impairments, respectively, at the post-ICU-MC. Additionally, 40%, 28%, 19%, and 2.5% had three, two, one, and none of these impairments, respectively. All patients experienced mental disorders and a decline in quality of life. Functional impairment correlated with frailty score and sex, and respiratory function with age. To conclude, the prevalence of PICS in our cohort was high, as was that of functional, respiratory and renal failure.
为了确定在 ICU 出院后约 3 个月接受 ICU 后多学科咨询（post-ICU-MC）的患者中功能性、呼吸和肾功能障碍以及 ICU 后综合征（PICS）的患病率，我们在法国克莱蒙费朗大学医院进行了一项回顾性、单中心观察性研究。我们纳入了参加过 post-ICU-MC 的患者。收集了他们在 ICU 期间和 post-ICU-MC 时的特征。通过 6 分钟步行试验、握力试验和峰吸气压评估功能状态，通过探索性功能结果评估呼吸功能，通过 SF-36 评分评估精神状态，通过 SF-36 评分和欧洲生活质量 5 维度问卷评估生活质量。总的来说，我们共纳入了 67 名患者，其中 70%、74%和 68%的患者在 post-ICU-MC 时存在功能性、呼吸性和肾功能障碍。此外，40%、28%、19%和 2.5%的患者分别有三种、两种、一种和没有这些障碍。所有患者都经历了精神障碍和生活质量下降。功能障碍与虚弱评分和性别相关，呼吸功能与年龄相关。总之，我们队列中 PICS 的患病率较高，功能性、呼吸性和肾功能衰竭的患病率也较高。
