• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

中国呼吸重症监护病房患者 ICU 后综合征的发生率及危险因素:一项横断面、前瞻性研究。

Incidence of and risk factors for post-intensive care syndrome among Chinese respiratory intensive care unit patients: A cross-sectional, prospective study.

机构信息

Peking University First Hospital, Beijing, China.

Peking University First Hospital, Beijing, China.

出版信息

Aust Crit Care. 2023 Jul;36(4):464-469. doi: 10.1016/j.aucc.2022.07.005. Epub 2022 Sep 11.

DOI:10.1016/j.aucc.2022.07.005
PMID:36104256
Abstract

BACKGROUND

Patients transferred from the respiratory intensive care unit (ICU) can experience post-intensive care syndrome (PICS), which comprises cognitive, psychological, and physical disorders that seriously affect the quality of life. Therefore, it was necessary to explore the incidence of and the risk factors for PICS among respiratory ICU patients.

OBJECTIVES

This study evaluated PICS among respiratory ICU patients and explored the risk factors for PICS.

METHODS

This cross-sectional, prospective study was performed at one hospital in China. Using convenience sampling, 125 respiratory ICU patients from August 2018 to June 2019 were recruited for the study. The Mini-Mental State Examination, Confusion Assessment Method for the Intensive Care Unit, Hospital Anxiety and Depression Scale, Medical Research Council Scale, activities of daily living scale, Pittsburgh Sleep Quality Index, and the 14-item fatigue scale were used to comprehensively assess the patients' cognitive status, psychological status, and physiological status when entering the ICU and 2 weeks after leaving the ICU. Factors affecting PICS were measured using researcher-created questionnaires of patients' general information and disease-related information.

RESULTS

Fifteen patients were lost to follow-up. Fifty-nine patients had PICS (incidence rate, 53.6%). Logistic regression showed that risk factors for PICS were age, invasive mechanical ventilation, noninvasive ventilator-assisted ventilation, and coronary heart disease (P < 0.05).

CONCLUSION

The PICS incidence was high. Older age, longer invasive mechanical ventilation times, longer noninvasive ventilator times, and coronary heart disease were risk factors for PICS. ICU medical workers in China should pay more attention on PICS, know the risk factors, and implement preventive measures.

摘要

背景

从呼吸重症监护病房(ICU)转出的患者可能会出现 ICU 后综合征(PICS),其包括认知、心理和身体障碍,严重影响生活质量。因此,有必要探讨呼吸 ICU 患者 PICS 的发生率及其危险因素。

目的

本研究评估了呼吸 ICU 患者的 PICS 发生率,并探讨了 PICS 的危险因素。

方法

这是一项在中国一家医院进行的横断面、前瞻性研究。采用便利抽样法,于 2018 年 8 月至 2019 年 6 月招募了 125 例呼吸 ICU 患者。采用简易精神状态检查、ICU 意识模糊评估法、医院焦虑抑郁量表、医学研究理事会量表、日常生活活动量表、匹兹堡睡眠质量指数和 14 项疲劳量表,全面评估患者进入 ICU 时和离开 ICU 后 2 周的认知状态、心理状态和生理状态。采用研究者自行设计的患者一般信息和疾病相关信息问卷,测量影响 PICS 的因素。

结果

15 例患者失访。59 例患者发生 PICS(发生率,53.6%)。Logistic 回归显示,PICS 的危险因素为年龄、有创机械通气、无创呼吸机辅助通气和冠心病(P<0.05)。

结论

PICS 发生率较高。年龄较大、有创机械通气时间较长、无创呼吸机通气时间较长和冠心病是 PICS 的危险因素。中国 ICU 医务人员应更加关注 PICS,了解危险因素,并采取预防措施。

相似文献

1
Incidence of and risk factors for post-intensive care syndrome among Chinese respiratory intensive care unit patients: A cross-sectional, prospective study.中国呼吸重症监护病房患者 ICU 后综合征的发生率及危险因素:一项横断面、前瞻性研究。
Aust Crit Care. 2023 Jul;36(4):464-469. doi: 10.1016/j.aucc.2022.07.005. Epub 2022 Sep 11.
2
Prevalence of post-intensive care syndrome among Japanese intensive care unit patients: a prospective, multicenter, observational J-PICS study.日本重症监护病房患者 ICU 后综合征的患病率:一项前瞻性、多中心、观察性 J-PICS 研究。
Crit Care. 2021 Feb 16;25(1):69. doi: 10.1186/s13054-021-03501-z.
3
Therapeutic respiratory and functional rehabilitation protocol for intensive care unit patients affected by COVID-19: a structured summary of a study protocol for a randomised controlled trial.针对感染新型冠状病毒肺炎(COVID-19)的重症监护病房患者的治疗性呼吸与功能康复方案:一项随机对照试验研究方案的结构化总结
Trials. 2021 Apr 12;22(1):268. doi: 10.1186/s13063-021-05210-y.
4
Post Intensive Care Syndrome (PICS) physical, cognitive, and mental health outcomes 6-months to 7 years after a major burn injury: A cross-sectional study.重度烧伤后6个月至7年的重症监护后综合征(PICS)的身体、认知和心理健康结局:一项横断面研究。
Burns. 2023 Feb;49(1):26-33. doi: 10.1016/j.burns.2022.10.004. Epub 2022 Nov 14.
5
Quality of life in ICU survivors and their relatives with post-intensive care syndrome: A systematic review.ICU 幸存者及其亲属的生活质量与 ICU 后综合征:系统评价。
Nurs Crit Care. 2024 Jul;29(4):807-823. doi: 10.1111/nicc.13077. Epub 2024 Apr 15.
6
Instruments to assess post-intensive care syndrome assessment: a scoping review and modified Delphi method study.评估 ICU 后综合征的评估工具:范围综述和改良 Delphi 方法研究。
Crit Care. 2023 Nov 7;27(1):430. doi: 10.1186/s13054-023-04681-6.
7
Inactivity May Identify Older Intensive Care Unit Survivors at Risk for Post-Intensive Care Syndrome.不活动可能会识别出老年重症监护病房幸存者患有重症监护后综合征的风险。
Am J Crit Care. 2024 Mar 1;33(2):95-104. doi: 10.4037/ajcc2024785.
8
Verifying the Japanese version of the Healthy Aging Brain Care Monitor self-report tool for evaluating post-intensive care syndrome.验证用于评估重症监护后综合征的健康老龄化大脑保健监测器自我报告工具的日文版。
Aust Crit Care. 2023 Nov;36(6):989-996. doi: 10.1016/j.aucc.2023.02.004. Epub 2023 Mar 16.
9
[Analysis of the risk factors of cognitive impairment in post-intensive care syndrome patient].[重症监护后综合征患者认知障碍的危险因素分析]
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2017 Aug;29(8):716-720. doi: 10.3760/cma.j.issn.2095-4352.2017.08.009.
10
Postintensive care syndrome in patients and family members. Analysis of COVID-19 and non-COVID-19 cohorts, with face-to-face follow-up at three months and one year.患者和家属的重症监护后综合征。COVID-19 和非 COVID-19 队列的分析,在三个月和一年时进行面对面随访。
Med Intensiva (Engl Ed). 2024 Aug;48(8):445-456. doi: 10.1016/j.medine.2024.04.004. Epub 2024 May 11.

引用本文的文献

1
Physical and Cognitive Impairments at ICU Discharge are Associated with High Long-Term Mortality in ICU Survivors with Solid Malignancies: A Retrospective Cohort Study.重症监护病房(ICU)出院时的身体和认知障碍与实体恶性肿瘤ICU幸存者的高长期死亡率相关:一项回顾性队列研究。
Ther Clin Risk Manag. 2025 Jul 21;21:1121-1133. doi: 10.2147/TCRM.S520206. eCollection 2025.
2
Supporting Post-ICU Recovery: A Narrative Review for General Practitioners.支持重症监护病房后的康复:全科医生的叙述性综述
Diseases. 2025 Jun 11;13(6):183. doi: 10.3390/diseases13060183.
3
Characteristics of symptoms and establishment of a predictive model for PICS in mechanically ventilated patients with severe pneumonia: a retrospective study.
机械通气的重症肺炎患者PICS的症状特征及预测模型的建立:一项回顾性研究
Eur J Med Res. 2025 Apr 10;30(1):264. doi: 10.1186/s40001-025-02547-x.
4
Risk prediction models for post-intensive care syndrome of ICU discharged patients: A systematic review.ICU 出院患者重症监护后综合征的风险预测模型:一项系统综述。
Int J Nurs Sci. 2024 Oct 16;12(1):81-88. doi: 10.1016/j.ijnss.2024.10.012. eCollection 2025 Jan.
5
Incidence of post-intensive care syndrome among patients admitted to post-ICU multidisciplinary consultations: the retrospective observational PICS-MIR study.ICU 后多学科会诊患者中 ICU 后综合征的发生率:回顾性观察性 PICS-MIR 研究。
Sci Rep. 2024 Nov 9;14(1):27389. doi: 10.1038/s41598-024-78686-8.
6
Post intensive care syndrome: A review of clinical symptoms, evaluation, intervention.重症监护后综合征:临床症状、评估及干预综述
Heliyon. 2024 May 17;10(10):e31278. doi: 10.1016/j.heliyon.2024.e31278. eCollection 2024 May 30.