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黏弹性测试是否应成为所有重症监护病房的标准床旁检测项目?

Should viscoelastic testing be a standard point-of-care test on all intensive care units?

作者信息

Natasha Passi Neha, Parker Thomas

机构信息

Whipps Cross University Hospital, Barts Health NHS Trust, London, UK.

出版信息

J Intensive Care Soc. 2024 Oct 15;25(4):432-439. doi: 10.1177/17511437241290154. eCollection 2024 Nov.

Abstract

Viscoelastic tests (VETs) have transformed assessment of haemostasis and transfusion practices in trauma, cardiac and liver transplantation centres. Impaired haemostasis is a common problem on the general intensive care unit (ICU), but routine use of VETs is rare. We have accordingly reviewed the evidence to determine whether there is evidence to support the use of VETs as a standard point of care test on all ICUs in assessing and managing patients. The benefits of using VETs in the management of major haemorrhage, namely faster identification of a coagulopathy, in particular early detection of fibrinolysis, and reduced transfusion requirements for blood products have been seen in the general ICU. Validation of treatments algorithms is now required to standardise practice. There is also emerging evidence to support the use of VETs to guide urgent treatment decisions in patients with a coagulopathy or in patients taking anti-coagulants or anti-platelet therapies. We recommend that departments independently review the feasibility of setting up a viscoelastic point of care service which considers the applicability to their patient cohort, the financial cost and the personnel required.

摘要

粘弹性检测(VETs)已经改变了创伤、心脏和肝移植中心的止血评估及输血实践。止血功能受损在普通重症监护病房(ICU)是一个常见问题,但VETs的常规使用却很少见。因此,我们回顾了相关证据,以确定是否有证据支持在所有ICU中将VETs作为评估和管理患者的标准床旁检测方法。在普通ICU中,使用VETs管理大出血的益处已得到证实,即能更快地识别凝血病,尤其是早期检测纤维蛋白溶解,并减少血液制品的输血需求。现在需要对治疗算法进行验证,以使实践标准化。也有新出现的证据支持使用VETs来指导凝血病患者或服用抗凝剂或抗血小板治疗患者的紧急治疗决策。我们建议各科室独立评估建立粘弹性床旁检测服务的可行性,这需要考虑其对患者群体的适用性、财务成本和所需人员。

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