State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, P. R. China.
School of Biological and Chemical Engineering, NingboTech University, Ningbo 315100, P. R. China.
ACS Sens. 2024 Nov 22;9(11):6148-6156. doi: 10.1021/acssensors.4c02009. Epub 2024 Nov 12.
The detection of acetone in human exhaled breath is crucial for the noninvasive diagnosis of diabetes. However, the direct and reliable detection of acetone in exhaled breath with high humidity at the parts per billion level remains a great challenge. Here, an ultrasensitive acetone gas sensor based on a K/Sn-CoO porous microsphere was reported. The sensor demonstrates a detection limit of up to 100 ppb, along with excellent repeatability and selectivity. Remarkably, without the removal of water vapor from exhaled breath, the sensor can accurately distinguish diabetic patients and healthy individuals according to the difference in acetone concentrations, demonstrating its great potential for diabetes diagnosis. The enhanced sensitivity of the sensor is attributed to the increased oxygen adsorption on the material surface due to K/Sn codoping and the stronger coadsorption of Sn-K atoms to acetone molecules. These findings shed light on the mechanisms underlying the sensor's improved performance.
在人体呼气中检测丙酮对于非侵入性诊断糖尿病至关重要。然而，在高湿度条件下直接且可靠地检测呼出气体中的丙酮，达到十亿分之几的水平，仍然是一个巨大的挑战。在此，报道了一种基于 K/Sn-CoO 多孔微球的超灵敏丙酮气体传感器。该传感器的检测限低至 100ppb，具有出色的重复性和选择性。值得注意的是，该传感器无需去除呼气中的水蒸气，即可根据丙酮浓度的差异准确区分糖尿病患者和健康个体，表明其在糖尿病诊断方面具有巨大的应用潜力。传感器灵敏度的增强归因于 K/Sn 共掺杂导致材料表面氧吸附增加，以及 Sn-K 原子对丙酮分子的协同吸附增强。这些发现揭示了传感器性能提高的机制。
