John Hunter Children's Hospital, Lookout Road, New Lambton Heights, NSW 2305, Australia; School of Medicine and Public Health, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia; Hunter Medical Research Institute, 1 Kookaburra Cct, New Lambton Heights, NSW 2305, Australia.
John Hunter Children's Hospital, Lookout Road, New Lambton Heights, NSW 2305, Australia; School of Medicine and Public Health, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia; Hunter Medical Research Institute, 1 Kookaburra Cct, New Lambton Heights, NSW 2305, Australia.
J Diabetes Complications. 2024 Dec;38(12):108904. doi: 10.1016/j.jdiacomp.2024.108904. Epub 2024 Nov 6.
To determine the prevalence of disordered eating behaviors (DEB) in a population of Australian adolescents with T1D and to investigate clinical parameters, insulin pump therapy (IPT) and continuous glucose monitor (CGM) data trends, and psychological attributes associated with DEB.
50 participants (27 female, 23 male, average age 15.2 years, average duration of diabetes 6.2 years) were recruited. Diabetes Eating Problem Survey-Revised (DEPS-R) and Strengths and Difficulties Questionnaires were completed. Prevalence of disordered eating was reported, and associations with clinical parameters, insulin pump therapy (IPT) and continuous glucose monitor (CGM) metrics were assessed.
Twenty-four participants (48 %) had an elevated DEPS-R score. Participants with elevated DEPS-R were more likely to be female (75 % vs 31.6 %, p = 0.004), have a higher HbA1c (8.2 %/67 mmol/mol vs. 6.9 %/51 mmol/mol, p < 0.002) and BMI Z-score (+1.28 SD vs +0.76 SD, p = 0.040). They had lower time in range, 3.9-10 mmol/L (50.3 % vs. 63.8 %, p = 0.01) and higher mean glucose (10.0 mmol/L vs. 8.3 mmol/L, p = 0.005). Of the 60 % using IPT, participants with elevated DEPS-R had increased meal bolus overrides (7.9 % vs 3.8 %, p = 0.047). Reported difficulties on SDQ were higher in the elevated DEPS-R group (18.3 vs 10.5, p < 0.002).
DEB are common in Australian adolescents with T1D and associated with increased dysglycemia. Diabetes technology cannot be solely relied upon for detection of DEB and there remains a need for routine screening.
确定澳大利亚青少年 1 型糖尿病患者中饮食紊乱行为（DEB）的流行情况，并研究临床参数、胰岛素泵治疗（IPT）和连续血糖监测（CGM）数据趋势以及与 DEB 相关的心理特征。
招募了 50 名参与者（27 名女性，23 名男性，平均年龄 15.2 岁，平均糖尿病病程 6.2 年）。完成糖尿病饮食问题调查修订版（DEPS-R）和长处和困难问卷。报告饮食紊乱的流行情况，并评估与临床参数、胰岛素泵治疗（IPT）和连续血糖监测（CGM）指标的关联。
24 名参与者（48%）DEPS-R 评分升高。DEPS-R 评分升高的参与者更有可能是女性（75%比 31.6%，p=0.004），糖化血红蛋白（HbA1c）更高（8.2%/67mmol/mol 比 6.9%/51mmol/mol，p<0.002）和 BMI Z 评分更高（+1.28 SD 比+0.76 SD，p=0.040）。他们的血糖达标时间更短（3.9-10mmol/L 为 50.3%比 63.8%，p=0.01），平均血糖更高（10.0mmol/L 比 8.3mmol/L，p=0.005）。在使用 IPT 的 60%的参与者中，DEPS-R 评分升高的参与者的餐时推注量更高（7.9%比 3.8%，p=0.047）。在 DEPS-R 评分升高的组中，SDQ 报告的困难更高（18.3 比 10.5，p<0.002）。
DEB 在澳大利亚青少年 1 型糖尿病患者中很常见，与血糖控制不佳有关。糖尿病技术不能仅用于检测 DEB，仍需要常规筛查。
