Kalashnikova L A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(1):24-8.
The authors compared the localization of cerebral strokes and the state of the carotid arteries in 46 patients with arterial hypertension in combination with atherosclerosis. Occlusion of the internal carotid artery was associated with infarcts of various size in the cortex and the subcortical substance of the brain. When there was a good collateral blood flow along the anastomoses of the cerebral surface from the posterior cerebral artery into the system of occluded internal carotid artery, these were small infarcts in the white substance of the frontal lobes which were not lacunar. The major importance in the development of cerebral strokes in cases of occluded internal carotid artery belongs to atherosclerosis. Small deep (lacunar) infarcts develop in cases of complete patency of the carotid arteries and the leading role in their genesis belongs to changes in the intracerebral arteries characteristic of arterial hypertension rather than to atherosclerotic lesion of the major arteries of the head. Thus, localization of cerebral infarctions in arterial hypertension combined with atherosclerosis is determined by the state of the carotid arteries and characteristics of the collateral circulation while any of the diseases may play the leading role in their development.
作者比较了46例患有动脉高血压合并动脉粥样硬化患者的脑卒中年发病部位及颈动脉状况。颈内动脉闭塞与大脑皮质及皮质下不同大小的梗死灶相关。当沿脑表面吻合支从大脑后动脉至闭塞的颈内动脉系统有良好的侧支血流时,额叶白质会出现非腔隙性的小梗死灶。颈内动脉闭塞时,动脉粥样硬化在脑卒中的发生中起主要作用。在颈动脉完全通畅的情况下会出现小的深部(腔隙性)梗死灶,其发生的主要原因是动脉高血压所特有的脑内动脉变化,而非头部主要动脉的动脉粥样硬化病变。因此,动脉高血压合并动脉粥样硬化时脑梗死的部位取决于颈动脉状况及侧支循环特点,而任何一种疾病在其发展过程中都可能起主导作用。