Fergusson R J, Atherden S M, McCrae W M, Edwards C R
Acta Paediatr Scand. 1986 Jan;75(1):124-7. doi: 10.1111/j.1651-2227.1986.tb10168.x.
Aldosterone was measured in the saliva of 20 patients with cystic fibrosis and a group of 20 normal children matched for age and sex. Mean levels were higher in the patient group but overall differences were small and statistically not significant. For the first time a link between aldosterone level and disease severity in patients with cystic fibrosis was established using a simple scoring system to assess disease activity. Urinary and salivary electrolytes were similar in the two groups. The results do not support the proposed hypothesis that the salivary glands of patients with cystic fibrosis are insensitive to aldosterone.
对20名囊性纤维化患者以及20名年龄和性别匹配的正常儿童的唾液进行了醛固酮测定。患者组的平均水平较高，但总体差异较小且无统计学意义。首次使用简单评分系统评估疾病活动度，建立了囊性纤维化患者醛固酮水平与疾病严重程度之间的联系。两组的尿液和唾液电解质相似。结果不支持所提出的假设，即囊性纤维化患者的唾液腺对醛固酮不敏感。
