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肾上腺结节评估中的定量成像生物标志物

Quantitative imaging biomarkers in the assessment of adrenal nodules.

作者信息

Yalon Mariana, Navin Patrick J

机构信息

Mayo Clinic, Rochester, USA.

出版信息

Abdom Radiol (NY). 2025 May;50(5):2169-2180. doi: 10.1007/s00261-024-04671-4. Epub 2024 Nov 13.

DOI:10.1007/s00261-024-04671-4
PMID:39532734
Abstract

Incidental adrenal nodules provide a diagnostic conundrum. Current imaging techniques have demonstrated success in identifying lipid-rich adenomas, however, are limited in detecting malignancy and assessing for functionality. Imaging biomarkers are objective characteristics derived from imaging that may measure normal or pathological processes or assess response to therapy. Recent attempts have been made to standardize the measurement of the most common imaging biomarkers used in assessing the adrenal gland, offering a path to more uniform research in this area. The aim of this review is to describe the imaging biomarkers used in adrenal imaging and assess the evidence supporting their use.

摘要

偶然发现的肾上腺结节带来了诊断难题。目前的成像技术在识别富含脂质的腺瘤方面已取得成功,然而,在检测恶性肿瘤和评估功能方面存在局限性。成像生物标志物是源自成像的客观特征,可测量正常或病理过程或评估对治疗的反应。最近已尝试对评估肾上腺时使用的最常见成像生物标志物的测量进行标准化,为该领域更统一的研究提供了一条途径。本综述的目的是描述肾上腺成像中使用的成像生物标志物,并评估支持其使用的证据。

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