Department of Urology, University Hospital del Vinalopó, Elche, Alicante, Spain.
University of Cambridge NHS Foundation Trust, Cambridge, UK.
World J Urol. 2024 Nov 12;42(1):638. doi: 10.1007/s00345-024-05334-1.
To assess the time taken by the single use 7.5Fr suction flexible ureteroscope to reduce pressure under 40 mm Hg and to characterize the behavior of stones, fragments and dust during suction activation.
An in vitro setting was developed for this experiment. A saline-filled globe, with the 7.5Fr single-use suction flexible ureteroscope, PU3033AH (ZhuHai Pusen Medical Technology Co, Ltd, Guangdon, China), an automatic irrigation pump and a pressure monitoring set were used at four modalities; i) continuous suction, no irrigation inflow; ii) continuous suction, irrigation inflow on; iii) one-second rate intermittent suction, irrigation inflow on, and iv) half-second rate intermittent suction, irrigation inflow on. The behavior of calcium oxalate stones from 0.5 to 5 mm when being aspirated via the ureteroscope into a plastic container filled with saline was recorded.
Suction with the PU3033AH worked properly with the inflow irritation on. The fastest strategy to lower the pressure was by continuously pressing the suction button with the irrigation inflow on. Overall, the median time to reach 40 mg was roughly 3.5 s. The PU3033AH could aspirate 0.5 mm stones. The suction mode on a continuous pattern allowed the relocation of stones ranging from 1 to 5 mm on an experimental setup with no obstacles.
The PU3033AH was efficient in lowering pressure in a closed cavity mimicking the renal pelvis. Likewise, stone fragments under one millimeter were aspirated by the device whereas stones from one to five mm could be displaced when activating suction in continuous mode on an experimental setup with no obstacles.
评估一次性使用 7.5Fr 吸引导管在将压力降低至 40mmHg 以下所需的时间，并描述在抽吸激活过程中结石、碎片和灰尘的行为。
为此实验开发了一种体外设置。使用充满生理盐水的球体、7.5Fr 一次性使用吸引导管（珠海普盛医疗科技有限公司，广东）、自动冲洗泵和压力监测套件，在以下四种模式下进行实验：i）连续抽吸，无冲洗流入；ii）连续抽吸，冲洗流入；iii）每秒一次间歇抽吸，冲洗流入；iv）每秒半次间歇抽吸，冲洗流入。记录了直径为 0.5 至 5mm 的草酸钙结石通过输尿管镜吸入充满生理盐水的塑料容器中的行为。
PU3033AH 在有冲洗流入刺激的情况下能够正常抽吸。降低压力最快的策略是在冲洗流入的情况下持续按下抽吸按钮。总体而言，达到 40mmHg 的中位时间约为 3.5s。PU3033AH 可以抽吸 0.5mm 的结石。在无障碍物的实验设置中，连续抽吸模式允许 1 至 5mm 的结石重新定位。
PU3033AH 能够有效地降低模拟肾盂的封闭腔体内的压力。同样，该设备可以抽吸直径小于 1 毫米的结石碎片，而当在无障碍物的实验设置中以连续模式激活抽吸时，1 至 5mm 的结石可以被移位。
