非小细胞肺癌脑转移的治疗：临床前、临床及转化研究
Treatment of brain metastases from non-small cell lung cancer: preclinical, clinical, and translational research.
作者信息
Sampat Parth J, Cortese Alyssa, Goodman Alexandra, Ghelani Ghanshyam H, Mix Michael D, Graziano Stephen, Basnet Alina
机构信息
Division of Hematology and Medical Oncology, Department of Medicine, SUNY Upstate Medical University, Syracuse, NY, United States.
Department of Radiation Oncology, SUNY Upstate Medical University, Syracuse, NY, United States.
出版信息
Front Oncol. 2024 Oct 29;14:1411432. doi: 10.3389/fonc.2024.1411432. eCollection 2024.
Lung cancer is the second most common type of cancer and is the leading cause of cancer-related deaths in the United States. Approximately 10-40% of patients with solid tumors develop brain metastases, with non-small cell lung cancer accounting for approximately 50% of all cases of patients with brain metastases. Many management options are available which can include surgery, radiation, and systemic therapy. A variety of factors go into the selection of management of brain metastases. In this review, we will focus on the treatment strategies and optimizing the management of brain metastases in patients with non-small cell lung cancer.
肺癌是第二常见的癌症类型，也是美国癌症相关死亡的主要原因。约10%-40%的实体瘤患者会发生脑转移，其中非小细胞肺癌约占所有脑转移患者病例的50%。有多种治疗选择，包括手术、放疗和全身治疗。脑转移的治疗选择涉及多种因素。在本综述中，我们将聚焦于非小细胞肺癌患者脑转移的治疗策略及优化管理。
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