Hong Min, Lin Ziying, Zhong Hua, Zhang Yan, Yang Dan, Zhong Sihui, Zhuang Xiangrong, Yue Xin
Department of Radiology, Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University, No. 2999 Jinshan Road, Huli District, Xiamen, 361004, Fujian Province, China.
Department of Radiology, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, No. 201-209 Hubinnan Road, Siming District, Xiamen, 361004, Fujian Province, China.
J Imaging Inform Med. 2024 Nov 13. doi: 10.1007/s10278-024-01330-4.
The objective of the study is to explore the image quality and diagnosis performance of the dual-energy CT-derived slope parameter images (SPI) generated by the algorithm based on the slope function in the diagnosis of Crohn's disease (CD). Seventy-six CD patients and 53 disease-free control group subjects who underwent dual-energy CT enterography were retrospectively collected. Portal venous phase 120kVp-like and virtual monoenergetic images at 40-100 keV (VMI) were reconstructed. SPIs corresponding to the spectral curve between 40 and 100 keV (SPI) were generated using Python. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of normal and abnormal intestinal walls were calculated. Image quality, noise, and contrast were independently scored by two radiologists using a 5-point scale. Four radiologists conducted CD diagnosis with three reading models (120kVp-like, 120kVp-like with optimal VMI, and 120kVp-like with SPI). The diagnostic performances of the three reading models for diagnosing CD were evaluated using receiver operating characteristic (ROC) curves. The CNR in SPI was higher than in the other images (P < 0.05). The subjective evaluation showed that there was no statistical difference between the contrast of SPI and VMI (P > 0.05), but that of the two images was higher than the other images (P < 0.05). The scoring on the overall image quality of VMI was superior to that of other images (P < 0.05). The combined model of 120kVp-like with SPI had the strongest confidence (cases with high confidence: 36, 58, 49, 47 for radiologists 1, 2, 3, 4) and the highest efficiency in diagnosing CD (areas under the ROC curve: 0.973, 0.977, 0.982, 0.991 for radiologists 1, 2, 3, 4). SPI generated by the algorithm based on the slope function exhibited good image quality. The combined model of 120kVp-like with SPI could improve radiologists' diagnostic efficiency and confidence in diagnosing CD.
本研究的目的是探讨基于斜率函数的算法生成的双能CT衍生斜率参数图像（SPI）在克罗恩病（CD）诊断中的图像质量和诊断性能。回顾性收集了76例接受双能CT小肠造影的CD患者和53例无病对照组受试者。重建门静脉期120kVp类似图像和40 - 100keV的虚拟单能图像（VMI）。使用Python生成对应于40至100keV光谱曲线的SPI。计算正常和异常肠壁的信噪比（SNR）和对比噪声比（CNR）。两名放射科医生使用5分制对图像质量、噪声和对比度进行独立评分。四名放射科医生采用三种读片模式（120kVp类似图像、120kVp类似图像加最佳VMI、120kVp类似图像加SPI）进行CD诊断。使用受试者操作特征（ROC）曲线评估三种读片模式对CD的诊断性能。SPI中的CNR高于其他图像（P < 0.05）。主观评估显示，SPI与VMI的对比度之间无统计学差异（P > 0.05），但这两种图像的对比度高于其他图像（P < 0.05）。VMI整体图像质量的评分优于其他图像（P < 0.05）。120kVp类似图像加SPI的联合模式具有最强的信心（放射科医生1、2、3、4的高信心病例数分别为36、58、49、47），且在诊断CD方面效率最高（放射科医生1、2、3、4的ROC曲线下面积分别为0.973、0.977、0.982、0.991）。基于斜率函数的算法生成的SPI表现出良好的图像质量。120kVp类似图像加SPI的联合模式可提高放射科医生对CD的诊断效率和信心。
