Nunes Batista Juliana Maria, Barbosa Guedes Israel, Messias Vila Emmanuel, Rodrigues Jorge Felipe, Bergmann Esteves Stephanie, Cavalcanti Brito João Eduardo, Carrillo Gaeta Natália, Gagete Veríssimo de Mello Beatriz, Mori Enio, Cortez Adriana, Augusto Dias Ricardo, Soares Ferreira Neto José, Bryan Heinemann Marcos
Laboratório de Zoonoses Bacterianas, Departamento de Medicina Veteriária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de Sâo Paulo, SP, Brazil.
Laboratório de Mamíferos, Departamento de Sistemática e Ecologia, Universidade Federal da Paraíba (CCEN/DSE), João Pessoa, PB, Brazil.
Microb Pathog. 2025 Jan;198:107117. doi: 10.1016/j.micpath.2024.107117. Epub 2024 Nov 13.
Bats play a crucial role in the ecosystem, yet concerns have arisen regarding their potential as carriers of zoonotic bacteria, including Leptospira spp. Due to the lack of knowledge about the carrier state of bats in Brazil, this study aimed to evaluate the presence of antibodies against Leptospira spp. and its DNA in bats from four Brazilian States (São Paulo, Paraíba, Pernambuco, and Ceará). Bats were captured using mist nets and categorized by sex, age, and species. Antibodies were searched in 22 bats via the microscopic agglutination test (MAT). Additionally, 168 kidney and nine urine samples were subjected to PCR for Leptospira spp. Out of 177 samples tested, two (1.13 %) were positive in PCR, while none showed reactivity in MAT. These results suggest a low prevalence of Leptospira spp. infection in bats, indicating a limited role in transmitting leptospirosis to humans, domestic animals, and wildlife in the studied region.
蝙蝠在生态系统中发挥着至关重要的作用，但人们对其作为包括钩端螺旋体属在内的人畜共患病细菌携带者的潜在风险产生了担忧。由于巴西对蝙蝠携带状态缺乏了解，本研究旨在评估来自巴西四个州（圣保罗、帕拉伊巴、伯南布哥和塞阿拉）的蝙蝠体内抗钩端螺旋体属抗体及其DNA的存在情况。使用雾网捕获蝙蝠，并按性别、年龄和物种进行分类。通过显微镜凝集试验（MAT）在22只蝙蝠中检测抗体。此外，对168份肾脏样本和9份尿液样本进行钩端螺旋体属的PCR检测。在177份检测样本中，两份（1.13%）PCR呈阳性，而MAT检测均无反应性。这些结果表明蝙蝠中钩端螺旋体属感染的患病率较低，表明在所研究地区，蝙蝠在将钩端螺旋体病传播给人类、家畜和野生动物方面的作用有限。
