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抗生素和凝集素C对仔猪腹泻控制的干预及影响。

Antibiotics and lectin C for diarrhea control intervention in piglets and influences.

作者信息

Trung Hoang Dinh, Hoang Ha Viet, Thong Nguyen Thach, Chitana Kenthalangsy, Hoai Dinh Thi Thu, Linh Nguyen Quang

机构信息

Faculty of Biology, University of Sciences, 77 Nguyen Hue St., Hue City, 530000, Vietnam.

Department of Animal Husbandry, Faculty of Animal Science and Veterinary Medicine of Biology, University of Agriculture and Forestry, Hue University, Hue City, 490000, Vietnam.

出版信息

AMB Express. 2024 Nov 14;14(1):126. doi: 10.1186/s13568-024-01775-4.

DOI:10.1186/s13568-024-01775-4
PMID:39542996
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11564646/
Abstract

The study was conducted on 60 L of suckling piglets out of 775 piglets, of which 227 piglets had diarrhea litres of piglets, and out of 775 piglets, 227 piglets had diarrhoea syndrome. There were 3 interventions in separate trials as follows: 1 and 2 involved antibiotic use (Enrofloxacin and Gentamicin); Trial 3 used the supplement Lectin C (LvCLT3 and LvCLT4) for a treatment period of 3-7 days. Intervention results on 227 piglets with diarrhea showed the highest cure rate when supplemented with Lectin C, with no mortality rate, longer treatment time, and no reinfection rate. While the two antibiotic trials still had lower cure rates, mortality and reinfection rates were higher. After 05 days of recovery, piglets were tested for MCV, MCH, and MCHC, showing an apparent decrease in the group supplemented with Lectin C, while the two groups using antibiotics still had high rates, with a confidence level of P < 0.05; 0.01 and 0.001. Antibiotics treat piglets in their early stages, so there is a risk of immunodeficiency and low infection response. It is necessary to supplement substances derived from dietary supplements. Supplementing Lectin C increases resistance, enhances immune response, improves the effectiveness of treating diarrhoea syndrome in piglets, and ensures safe meat quality in the future. Lectin C supplementation will improve piglet health and breed quality efficiency. This heralds a promising future for the pig industry with improved meat quality and reduced environmental impact.

摘要

该研究对775头仔猪中的60头哺乳仔猪进行,其中227头仔猪出现腹泻。在775头仔猪中,有227头仔猪患有腹泻综合征。在单独的试验中有3种干预措施,具体如下:干预措施1和2涉及使用抗生素(恩诺沙星和庆大霉素);试验3使用凝集素C补充剂(LvCLT3和LvCLT4),治疗期为3至7天。对227头腹泻仔猪的干预结果显示,补充凝集素C时治愈率最高,无死亡率、治疗时间更长且无再感染率。而两项抗生素试验的治愈率仍然较低,死亡率和再感染率较高。恢复05天后,对仔猪进行平均红细胞体积(MCV)、平均红细胞血红蛋白含量(MCH)和平均红细胞血红蛋白浓度(MCHC)检测,结果显示补充凝集素C的组明显下降,而使用抗生素的两组仍处于较高水平,置信水平为P < 0.05;0.01和0.001。抗生素在仔猪早期进行治疗,因此存在免疫缺陷和低感染反应的风险。有必要补充来自膳食补充剂的物质。补充凝集素C可增强抵抗力、提高免疫反应、提高治疗仔猪腹泻综合征的有效性,并确保未来猪肉质量安全。补充凝集素C将改善仔猪健康和养殖质量效率。这预示着养猪业有着前景光明的未来,猪肉质量得到改善,对环境的影响降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c2c/11564646/fa8159c75a01/13568_2024_1775_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c2c/11564646/43abecc123c8/13568_2024_1775_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c2c/11564646/fa8159c75a01/13568_2024_1775_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c2c/11564646/43abecc123c8/13568_2024_1775_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c2c/11564646/fa8159c75a01/13568_2024_1775_Fig2_HTML.jpg

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