Department of Ultrasound, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Department of Neonatal Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
BMC Pediatr. 2024 Nov 14;24(1):736. doi: 10.1186/s12887-024-05192-1.
Neonatal appendicitis is a rare but critical condition that presents diagnostic challenges due to its nonspecific symptoms and clinical manifestations. Early and accurate diagnosis is crucial for reducing the high mortality rates associated with this condition. Abdominal ultrasonography plays a pivotal role in identifying characteristic signs of appendicitis in neonates. This study aimed to investigate whether neonatal appendicitis can be diagnosed with abdominal ultrasonography by identifying its specific signs.
This study reviewed 20 consecutive cases of neonatal appendicitis confirmed through surgery at a National Medical Center. Preoperative abdominal ultrasonography was analyzed for direct and indirect signs of appendicitis.
Our study included neonates with a mean age of 13.0 ± 7.1 days. The appendix was identifiable in 13 out of 20 cases (65%). The mean outer diameter of the appendix was 4.6 ± 1.8 mm. Eight cases had appendix diameter ≥ 4 mm. Fluid accumulation within the appendiceal cavity was noted in 6 (30%) patients, and peri-appendiceal fluid accumulation was detected in 5 (25%) patients. Ultrasonography revealed appendiceal perforation in 12 out of 16 cases (75%). The indirect signs of neonatal appendicitis included right lower quadrant (RLQ) abscess, pneumoperitoneum, and thickening of the intestinal wall and mesentery in the RLQ.
Most cases of neonatal appendicitis may be diagnosed through abdominal ultrasonography by identifying both direct and indirect signs. Future studies with larger patient cohorts are needed to improve ultrasonographic diagnosis of neonatal appendicitis.
新生儿阑尾炎是一种罕见但危急的病症,由于其症状和临床表现不具特异性,诊断具有挑战性。早期、准确的诊断对于降低与该病症相关的高死亡率至关重要。腹部超声检查在识别新生儿阑尾炎的特征性征象方面发挥着关键作用。本研究旨在探讨是否可以通过识别其特定征象,利用腹部超声检查来诊断新生儿阑尾炎。
本研究回顾性分析了在一家国立医疗中心通过手术确诊的 20 例连续新生儿阑尾炎病例。对术前腹部超声检查进行分析,以识别阑尾炎的直接和间接征象。
本研究纳入的新生儿平均年龄为 13.0±7.1 天。20 例中,有 13 例(65%)可识别阑尾。阑尾外径平均为 4.6±1.8mm。8 例阑尾直径≥4mm。6 例(30%)患者阑尾腔内有积液,5 例(25%)患者阑尾周围有积液。16 例中有 12 例(75%)超声检查显示阑尾穿孔。新生儿阑尾炎的间接征象包括右下腹(RLQ)脓肿、气腹和 RLQ 处肠壁和肠系膜增厚。
通过识别直接和间接征象,大多数新生儿阑尾炎病例可通过腹部超声检查进行诊断。需要进一步开展具有更大患者队列的研究,以提高超声检查对新生儿阑尾炎的诊断水平。