Jenkins Timothy O, Sutton Thomas M, Griffen Peter, Mebrate Yoseph, Polkey Michael I
Harefield Respiratory Research Group, Royal Brompton and Harefield Clinical Group, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Department of Health Sciences, College of Health, Medicine and Life Sciences, Brunel University London, London, UK.
J Intensive Care Soc. 2024 Nov 4;26(1):112-114. doi: 10.1177/17511437241296685. eCollection 2025 Feb.
There are instances where hospitals may experience a relative shortage of oxygen, for example, future pandemics, natural disasters or wartime. We developed a modification to a domiciliary ventilator that captures oxygen normally vented during expiration into the atmosphere, delivering it to the patient. The modification significantly increases PaO in mechanically ventilated patients at their baseline FiO and baseline FiO +1, +2 and +3 L/min compared to no modification. The modification reduces walled oxygen consumption by median (IQR) -1.0 (-1.25 to -1.00) L/min whilst maintaining PaO. This modification may be a valuable in circumstances where there is a relative shortage of oxygen.
在某些情况下，医院可能会面临氧气相对短缺的情况，例如未来的大流行、自然灾害或战时。我们对家用呼吸机进行了改进，该改进可收集呼气时通常排放到大气中的氧气，并将其输送给患者。与未改进的情况相比，这种改进在机械通气患者的基线吸入氧浓度（FiO）以及基线FiO +1、+2和+3升/分钟时显著提高了动脉血氧分压（PaO）。该改进使壁式氧气消耗量中位数（四分位间距）降低了-1.0（-1.25至-1.00）升/分钟，同时维持了PaO。在氧气相对短缺的情况下，这种改进可能很有价值。
