MEDICent Klinika, Na Čtvrti 22, Ostrava, 700 30, Czech Republic.
Department of Burns and Plastic Surgery, University Hospital Brno and Medical Faculty of Masaryk University, Kamenice 5, Brno, Brno-Bohunice, 625 00, Czech Republic.
BMC Musculoskelet Disord. 2024 Nov 16;25(1):919. doi: 10.1186/s12891-024-08031-7.
Large femoral defects after trauma, femoral non-unions, fractures complicated by osteomyelitis or defects after bone tumour resection present high burden and increased morbidity for patient and are challenging for reconstructive surgeons. Defects larger than 6 cm and smaller defects after failed spongioplasty are suitable for reconstruction using a free, eventually a pedicled vascularised bone flap. The free fibular flap is preferred but an iliac crest free flap or a pedicled medial femoral condyle flap can be also used. These vascularised flaps are ideal for bridging defects of long bones and can be also used as osteocutaneous or osteomuscular flaps for coverage of soft tissue defect if present. The patients and their families were informed that data will be submitted for publication and they gave their written informed consent prior to the submission. The study was approved by the institutional ethic committee.
We analysed a group of eight patients with large diaphyseal or distal metaphyseal femoral defects. A free fibular flap was used in six patients, a pedicled medial ipsilateral femoral condyle flap was used in two patients and a defect in one patient was reconstructed using an iliac crest free flap.
All flaps healed completely in all patients and no fracture of the flap was detected during the study period. In one patient, a locking plate broke and was replaced by a compression plate. At the last check-up all patients were able to step on the reconstructed limb with full weight.
Although our study comprises a heterogeneous group of cases, they all have been successfully treated by a similar technique, adapted in each case specifically to the needs of the patient. A major limitation parameter of reconstruction by a free vascularised flap is the size of bone defect needed to be reconstructed. In case of a bone defect longer than 6 cm and a concomitant soft tissue disruption, a vascularised double-barrel fibula is the preferred.
Large femoral defects can be successfully reconstructed with good long-term results using suitable free or pedicled vascularised bone flaps, especially preferring the free fibular flap.
创伤后股骨大缺损、股骨不愈合、合并骨髓炎的骨折或骨肿瘤切除后的缺损给患者带来了高负担和增加发病率,对重建外科医生来说也是具有挑战性的。大于 6 厘米的缺损和骨水泥成形术失败后的小缺损适合使用游离的、最终带蒂的血管化骨瓣进行重建。游离腓骨瓣是首选,但也可以使用髂嵴游离瓣或带蒂股骨内侧髁瓣。这些血管化皮瓣非常适合桥接长骨缺损,如果存在,也可以作为骨皮瓣或骨肌皮瓣用于覆盖软组织缺损。在提交前,患者及其家属已被告知数据将提交发表,并签署了书面知情同意书。该研究已获得机构伦理委员会的批准。
我们分析了 8 例股骨骨干或远端干骺端大缺损患者。6 例患者采用游离腓骨瓣,2 例患者采用带蒂同侧股骨内侧髁瓣,1 例患者采用髂嵴游离瓣重建缺损。
所有患者的皮瓣均完全愈合,研究期间未发现皮瓣骨折。1 例患者锁定钢板断裂,更换为加压钢板。最后一次检查时,所有患者均能完全负重踩在重建的肢体上。
尽管我们的研究包括一组异质性病例,但所有病例均采用类似的技术成功治疗,根据患者的具体需要在每种情况下进行了具体调整。游离血管化皮瓣重建的一个主要限制参数是需要重建的骨缺损大小。在骨缺损长度大于 6 厘米且伴有软组织撕裂的情况下,首选血管化双段腓骨。
使用合适的游离或带蒂血管化骨瓣可以成功重建大的股骨缺损,长期效果良好,尤其是游离腓骨瓣。