Department of Periodontology, Faculty of Dentistry, Marmara University, İstanbul, Türkiye.
Department of Periodontology, Faculty of Dentistry, Bahçeşehir University, İstanbul, Türkiye.
BMC Oral Health. 2024 Nov 16;24(1):1395. doi: 10.1186/s12903-024-05207-4.
Dentin hypersensitivity (DH) affects many patients. Various therapeutic options have been devised to alleviate this condition by achieving dentinal tubules (DT) occlusion. This research aimed to investigate the effects of dipotassium oxalate-containing mouthwash, diode laser and their combination on DT occlusion.
Forty dentin samples were obtained from 20 human single-rooted third molars, 40 dentin specimens were obtained, and exposed DT were created in vitro. They were assigned into four groups: Group 1 (n = 10), the control group where no treatment was applied; Group 2 (n = 10), a mouthwash with a 1.4% dipotassium oxalate was applied twice for 60 s during a 5-day period in a shaker at 100 rpm; Group 3 (n = 10), a combination of the same mouthwash and an 810 nm diode laser at an output power of 0.25 W in continuous mode was applied for 60 s without contact at a distance of 3-4 mm; and Group 4 (n = 10), only a diode laser with the same protocol was applied. Occlusion of the DT was observed by scanning electron microscopy.
The analysis revealed occlusion of the DT in all treatment groups; however, the effects were more pronounced in the combined treatment group (Group 3). Compared with the test groups, the control group had significantly more open DT in 100 µm (p < 0.01). The difference between the Group 2 and Group 4 was not significant (p > 0.05).
DT occlusion was achieved via the use of a mouthwash containing 1.4% dipotassium oxalate and an 810 nm diode laser. However, the combination resulted in the greatest results and therefore may be utilized in individuals with DH.
牙本质敏感(DH)影响许多患者。已经设计了各种治疗选择,通过实现牙本质小管(DT)闭塞来缓解这种情况。本研究旨在研究含有草酸钾的漱口液、二极管激光及其组合对 DT 闭塞的影响。
从 20 个人的单根第三磨牙中获得 40 个牙本质样本,体外创建暴露的 DT。将它们分为四组:第 1 组(n=10),对照组,不应用任何治疗;第 2 组(n=10),在振荡器中以 100rpm 的速度用 1.4%草酸钾漱口液应用两次,每次 60s,为期 5 天;第 3 组(n=10),同一漱口液和 810nm 二极管激光的组合,在无接触的情况下以 3-4mm 的距离以连续模式应用 60s,输出功率为 0.25W;第 4 组(n=10),仅应用相同协议的二极管激光。通过扫描电子显微镜观察 DT 的闭塞情况。
分析显示所有治疗组的 DT 均有闭塞;然而,联合治疗组(第 3 组)的效果更为明显。与测试组相比,对照组在 100µm 处的 DT 明显更多(p<0.01)。第 2 组和第 4 组之间的差异不显著(p>0.05)。
通过使用含有 1.4%草酸钾的漱口液和 810nm 二极管激光可以实现 DT 闭塞。然而,联合治疗产生了最大的效果,因此可能用于 DH 患者。