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评估脱敏漱口水和常规漱口液促进牙本质小管封闭的能力。

Assessment of the Ability of Desensitizing and Conventional Mouth Rinses to Promote Dentin Tubule Occlusion.

机构信息

Diana Roberta Pereira Grandizoli, DDS, MSc, PhD student, University of São Paulo, São Paulo, Brazil.

Ana Luisa Meira Renzo, DDS, University of São Paulo, São Paulo, Brazil.

出版信息

Oper Dent. 2022 Sep 1;47(5):549-561. doi: 10.2341/21-043-L.

DOI:10.2341/21-043-L
PMID:36026699
Abstract

This study aimed to evaluate the effect of desensitizing and conventional mouth rinses on dentin tubule occlusion. Dentin hypersensitivity was simulated by EDTA application for five minutes. The specimens were randomly allocated into the following groups: desensitizing mouth rinses (Colgate Sensitive, Elmex Sensitive Professional, Listerine Advanced Defense Sensitive, Sensodyne Cool Mint); conventional mouth rinses (Colgate Plax, Elmex Caries Protection, Listerine Anticaries, Sensodyne Pronamel); a negative control (C-: distilled water); and Clinpro XT Varnish was the positive control (C+). Subsequently, the specimens were submitted to an erosive or abrasive challenge (performed separately) and to an erosive/abrasive cycling for five days (n=10 for each challenge). After treatment, challenges, and cycling, the specimens were analyzed in an environmental scanning electron microscope to verify the number of open dentin tubules (ODTs), counted by using Image J software (National Institutes of Health, Bethesda, MD, USA). Data were analyzed by the Kruskal-Wallis, Friedman and Dunn tests, with Bonferroni correction (α=0.05). Groups did not differ at baseline (p>0.05). At the post-treatment, erosion and abrasion stages, C+ was the only group that showed a reduction in ODTs compared to C-(p<0.05). In the other groups, numbers did not differ significantly from C- (p>0.05). After cycling, none of the groups exhibited significant reduction in ODTs other than C- (p>0.05); however, C+, Listerine Anticaries, and Colgate Plax had a lower number of ODTs than Listerine Sensitive and Sensodyne Pronamel. No mouth rinse was able to promote significant occlusion of the dentin tubules after treatment and the challenges. C+ was the only product that effectively promoted tubular occlusion, but this effect did not withstand several erosive and abrasive challenges.

摘要

本研究旨在评估脱敏漱口水和常规漱口水对牙本质小管封闭的效果。通过 EDTA 应用五分钟来模拟牙本质敏感。将标本随机分配到以下组别:脱敏漱口水(高露洁敏感、舒适达专业脱敏、李斯德林高级防护敏感、舒适达清凉薄荷);常规漱口水(高露洁全效、舒适达专业护齿、李斯德林防蛀、舒适达亮白);阴性对照(C-:蒸馏水);Clinpro XT 牙釉质保护剂为阳性对照(C+)。随后,将标本分别进行侵蚀或磨损挑战(单独进行),并进行为期五天的侵蚀/磨损循环(每种挑战各 10 个标本)。治疗、挑战和循环后,用环境扫描电子显微镜分析标本,使用 Image J 软件(美国国立卫生研究院,贝塞斯达,MD)计算开放牙本质小管(ODTs)的数量。采用 Kruskal-Wallis、Friedman 和 Dunn 检验进行数据分析,并用 Bonferroni 校正(α=0.05)。各组在基线时无差异(p>0.05)。在治疗后、侵蚀和磨损阶段,C+是唯一一组与 C-相比 ODTs 减少的组(p<0.05)。在其他组中,与 C-相比,数值无显著差异(p>0.05)。在循环后,除 C-外,其他组的 ODTs 均无显著减少(p>0.05);然而,C+、李斯德林防蛀和高露洁全效的 ODTs 数量少于李斯德林敏感和舒适达亮白。没有漱口水在治疗和挑战后能够显著封闭牙本质小管。C+是唯一有效促进管腔封闭的产品,但这种效果无法承受多次侵蚀和磨损挑战。

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