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禽肉产品中的抗生素残留与细菌耐药性:发展中国家的综述

Antibiotic residues in poultry products and bacterial resistance: A review in developing countries.

机构信息

Holy Spirit University of Kaslik, Faculty of Arts and Sciences, Biology Department, B.P. 446 Jounieh, Lebanon.

Modern University for Business and Science, Faculty of Health Sciences, Lebanon.

出版信息

J Infect Public Health. 2024 Dec;17(12):102592. doi: 10.1016/j.jiph.2024.102592. Epub 2024 Nov 12.

Abstract

Antimicrobial resistance (AMR) is a growing global concern, particularly in poultry farming, where antibiotics are widely used for both disease prevention and growth promotion. This review examines the misuse of antibiotics in poultry production, especially in developing countries, and its contribution to the emergence of antibiotic-resistant bacteria. The findings highlight that factors such as increasing demand for poultry protein, the availability of inexpensive antibiotics, and weak regulatory oversight have led to widespread misuse, accelerating the spread of resistance genes. Although evidence links poultry farming to AMR, significant data gaps remain, especially regarding resistance transmission from poultry to humans. The review underscores the urgent need for stronger regulatory frameworks, phased-out use of antimicrobial growth promoters, and enhanced awareness campaigns to address this issue. Improving the capacity of regulatory bodies and developing more robust national data monitoring systems are essential steps to mitigate the threat of AMR in poultry farming and to protect both animal and human health.

摘要

抗微生物药物耐药性(AMR)是一个日益严重的全球性问题,特别是在禽畜养殖领域,抗生素被广泛用于疾病预防和促进生长。本综述审视了抗生素在禽畜养殖中的不当使用,尤其是在发展中国家,及其对抗生素耐药菌出现的贡献。研究结果表明,对禽畜蛋白需求的增加、廉价抗生素的供应,以及监管监督的薄弱等因素导致了抗生素的广泛滥用,加速了耐药基因的传播。尽管有证据表明禽畜养殖与 AMR 有关,但仍存在重大数据空白,特别是关于耐药性从禽畜向人类传播的情况。本综述强调了迫切需要更强有力的监管框架、逐步淘汰抗菌生长促进剂的使用,以及加强宣传活动来解决这一问题。提高监管机构的能力并开发更强大的国家数据监测系统是缓解禽畜养殖中 AMR 威胁以及保护动物和人类健康的必要步骤。

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