Bonithon-Kopp C, Huel G, Grasmick C, Sarmini H, Moreau T
Biol Res Pregnancy Perinatol. 1986;7(1):37-42.
Blood samples to be analysed for lead, cadmium and mercury were taken from 417 pregnant women not occupationally exposed to these metals. Each subject was paired with a non-pregnant woman of the same age (+/- 2 years), socio-economic status, alcohol and tobacco status. Most of the inter-individual variations observed in earlier studies were confirmed in the control group. Among the pregnant women, however, such variations in blood metal levels appeared to be somewhat different compared to the control women according to the parameters studied: age of the women, alcohol and tobacco consumption. Furthermore, the study of the evolution of blood levels of lead, cadmium and mercury throughout pregnancy revealed a significant decrease in cadmium levels during the first half of pregnancy. A similar tendency was observed for lead but this did not attain statistical significance.
从417名未从事接触这些金属职业的孕妇身上采集了用于分析铅、镉和汞的血样。将每位受试者与一名年龄相同（±2岁）、社会经济地位、饮酒和吸烟状况相同的非孕妇配对。早期研究中观察到的大多数个体间差异在对照组中得到了证实。然而，在孕妇中，根据所研究的参数（女性年龄、饮酒和吸烟情况），血金属水平的此类差异与对照女性相比似乎有所不同。此外，对整个孕期铅、镉和汞血水平变化的研究表明，孕期前半段镉水平显著下降。铅也观察到类似趋势，但未达到统计学显著性。
